Research to understand human genomic variation and its implications in health has great
potential to contribute in the reduction of health disparities. Biological anthropology can play …

Aims A polygenic risk score (PRS) has the potential to improve individual atherosclerotic
cardiovascular disease (ASCVD) risk assessment. To determine whether a PRS combined …

Background Little is known about whether the association between genetic susceptibility to
high waist-to-hip ratio (WHR), a measure of abdominal obesity, and incident coronary heart …

Most traits in livestock, crops and humans are polygenic, that is, a large number of loci
contribute to genetic variation. Effects at these loci lie along a continuum ranging from …

Risk factor–based models fail to accurately estimate risk in select populations, in particular
younger individuals. A sizable number of people are also classified as being at intermediate …

The increased prevalence of childhood obesity is expected to translate in the near future into
a concomitant soaring of multiple cardio-metabolic diseases. Obesity has a complex …

Background: Disordered eating (DE) is common and is associated with body mass index
(BMI). We investigated whether genetic variants for BMI were associated with DE. Methods …

The use of genomic information to better understand and prevent common complex
diseases has been an ongoing goal of genetic research. Over the past few years, research …

The predictive performance of polygenic scores (PGS) is largely dependent on the number
of samples available to train the PGS. Increasing the sample size for a specific phenotype is …

Genome‐wide association studies (GWAS) have identified many genetic risk variants for
cancers. The utility of these variants in assessing risk of esophageal, gastric and …