Outpatient randomized controlled trials to reduce COVID‐19 hospitalization: Systematic review and meta‐analysis

DJ Sullivan, D Focosi, DF Hanley… - Journal of Medical …, 2023 - Wiley Online Library
This COVID‐19 outpatient randomized controlled trials (RCTs) systematic review compares
hospitalization outcomes amongst four treatment classes over pandemic period, geography …

Viral clearance as a surrogate of clinical efficacy for COVID-19 therapies in outpatients: a systematic review and meta-analysis

KM Elias, SR Khan, E Stadler, TE Schlub… - The Lancet …, 2024 - thelancet.com
Background Surrogates of antiviral efficacy are needed for COVID-19. We aimed to
investigate the relationship between the virological effect of treatment and clinical efficacy as …

Virologic efficacy of casirivimab and imdevimab COVID-19 antibody combination in outpatients with SARS-CoV-2 infection: a phase 2 dose-ranging randomized …

C Portal-Celhay, E Forleo-Neto, W Eagan… - JAMA Network …, 2022 - jamanetwork.com
Importance The monoclonal antibody combination of casirivimab and imdevimab reduced
viral load, hospitalization, or death when administered as a 1200-mg or greater intravenous …

[HTML][HTML] Outpatient regimens to reduce COVID-19 hospitalisations: a systematic review and meta-analysis of randomized controlled trials

DJ Sullivan, D Focosi, DF Hanley, M Cruciani… - MedRxiv, 2023 - ncbi.nlm.nih.gov
Background During pandemics, early outpatient treatments reduce the health system
burden. Randomized controlled trials (RCTs) in COVID-19 outpatients have tested …

Current Therapeutic Strategies and Possible Effective Drug Delivery Strategies against COVID-19

DG Dastidar, D Ghosh, S Ghosh… - Current Drug …, 2023 - ingentaconnect.com
COVID-19 pandemic is the biggest global crisis. The frequent mutations in coronavirus to
generate new mutants are of major concern. The pathophysiology of SARS-CoV-2 infection …