Statin use for the primary prevention of cardiovascular disease in adults: updated evidence report and systematic review for the US Preventive Services Task Force

R Chou, A Cantor, T Dana, J Wagner, AY Ahmed, R Fu… - Jama, 2022 - jamanetwork.com
Importance A 2016 review for the US Preventive Services Task Force (USPSTF) found use
of statins for primary prevention of cardiovascular disease (CVD) was associated with …

2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: a report of the American College of …

SM Grundy, NJ Stone, AL Bailey, C Beam, KK Birtcher… - Circulation, 2019 - Am Heart Assoc
The American Heart Association requests that this document be cited as follows: Grundy SM,
Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, Braun LT, de Ferranti S, Faiella …

[HTML][HTML] Cardiovascular risk factors and physical activity for the prevention of cardiovascular diseases in the elderly

L Ciumărnean, MV Milaciu, V Negrean… - International Journal of …, 2021 - mdpi.com
Cardiovascular diseases create an important burden on the public health systems,
especially in the elderly, mostly because this group of patients frequently suffer from multiple …

Characteristics, prevention, and management of cardiovascular disease in people living with HIV: a scientific statement from the American Heart Association

MJ Feinstein, PY Hsue, LA Benjamin, GS Bloomfield… - Circulation, 2019 - Am Heart Assoc
As early and effective antiretroviral therapy has become more widespread, HIV has
transitioned from a progressive, fatal disease to a chronic, manageable disease marked by …

Association of statin use with all-cause and cardiovascular mortality in US veterans 75 years and older

AR Orkaby, JA Driver, YL Ho, B Lu, L Costa… - Jama, 2020 - jamanetwork.com
Importance Data are limited regarding statin therapy for primary prevention of atherosclerotic
cardiovascular disease (ASCVD) in adults 75 years and older. Objective To evaluate the …

Ezetimibe lipid-lowering trial on prevention of atherosclerotic cardiovascular disease in 75 or older (ewtopia 75) A randomized, controlled trial

Y Ouchi, J Sasaki, H Arai, K Yokote, K Harada… - Circulation, 2019 - Am Heart Assoc
Background: Evidence regarding the primary prevention of coronary artery disease events
by low-density lipoprotein cholesterol (LDL-C) lowering therapy in older individuals, aged≥ …

Statins for primary prevention of cardiovascular events and mortality in old and very old adults with and without type 2 diabetes: retrospective cohort study

R Ramos, M Comas-Cufí, R Martí-Lluch, E Balló… - bmj, 2018 - bmj.com
Objective To assess whether statin treatment is associated with a reduction in
atherosclerotic cardiovascular disease (CVD) and mortality in old and very old adults with …

[HTML][HTML] International Group for Reducing Inappropriate Medication Use & Polypharmacy (IGRIMUP): position statement and 10 recommendations for action

D Mangin, G Bahat, BA Golomb, LH Mallery… - Drugs & aging, 2018 - Springer
Globally, the number of drug prescriptions is increasing causing more adverse drug events,
which is now a significant cause of mortality, morbidity, and disability that has reached …

Cardiovascular effect of discontinuing statins for primary prevention at the age of 75 years: a nationwide population-based cohort study in France

P Giral, A Neumann, A Weill, J Coste - European heart journal, 2019 - academic.oup.com
Aims The role of statin therapy in primary prevention of cardiovascular disease in persons
older than 75 years remains a subject of debate with little evidence to support or exclude the …

Association of low‐density lipoprotein cholesterol levels with more than 20‐year risk of cardiovascular and all‐cause mortality in the general population

S Rong, B Li, L Chen, Y Sun, Y Du, B Liu… - Journal of the …, 2022 - Am Heart Assoc
Background Current cholesterol guidelines have recommended very low low‐density
lipoprotein cholesterol (LDL‐C) treatment targets for people at high risk of cardiovascular …