Thrombosis is the most feared complication of cardiovascular diseases and a main cause of
death worldwide, making it a major health-care challenge. Platelets and the coagulation …

The Covid-19 pandemic has introduced an array of organspecific and systemic phenotypes-
some previously observed in viral infections, including severe acute respiratory syndrome …

Platelets—blood cells continuously produced from megakaryocytes mainly in the bone
marrow—are implicated not only in haemostasis and arterial thrombosis, but also in other …

Non-alcoholic fatty liver disease ranges from steatosis to non-alcoholic steatohepatitis
(NASH), potentially progressing to cirrhosis and hepatocellular carcinoma (HCC). Here, we …

Neutrophils are well known for their role in infection and inflammatory disease and are first
responders at sites of infection or injury. Platelets have an established role in hemostasis …

In this paper, a model is proposed of the pathophysiological processes of COVID-19 starting
from the infection of human type II alveolar epithelial cells (pneumocytes) by SARS-CoV-2 …

Platelets are increasingly being recognized for playing roles beyond thrombosis and
hemostasis. Today we know that they mediate inflammation by direct interactions with innate …

Beyond platelets function in hemostasis, there is emerging evidence to suggest that platelets
contribute crucially to inflammation and immune responses. Therefore, considering the …

Beyond their role in hemostasis and thrombosis, platelets are increasingly recognized as
key regulators of the inflammatory response under sterile and infectious conditions. Both …

We investigated the contribution of human platelets to macrophage effector properties in the
presence of lipopolysaccharide (LPS), as well as the beneficial effects and time frame for …