Individuals infected with P. falciparum develop antibody responses to intra-erythrocytic
gametocyte proteins and exported gametocyte proteins present on the surface of infected …

Vector-borne diseases (VBDs) are a significant and growing threat to the health of the 326
million people living in the Greater Mekong Subregion (GMS)(Fig 1). The GMS is a diverse …

A century of conceptual and technological advances in infectious disease research has
changed the face of medicine. However, there remains a lack of effective interventions and a …

ABSTRACT Group A Streptococcus (GAS) is a major cause of global infection-related
morbidity and mortality. A modern controlled human infection model (CHIM) of GAS …

Considerable progress has been made in malaria control in the last two decades, but
progress has stalled in the last few years. New tools are needed to achieve public health …

Ethnopharmacological relevance Milk production, processing and consumption are integral
part of traditional practices in Fulani tribe of Cameroon. It has been observed that Fulani are …

In the absence of clinically proven vaccines and emerging resistance to common
antimalarials and insecticides, the onus of interrupting the life cycle of Plasmodium …

RTS, S/AS01 (GSK) is the world's first malaria vaccine. However, despite initial efficacy of
almost 70% over the first 6 months of follow-up, efficacy waned over time. A deeper …

Plasmodium knowlesi, a model malaria parasite, is responsible for a significant portion of
zoonotic malaria cases in Southeast Asia and must be controlled to avoid disease severity …

Background Human infection studies (HIS) that involve deliberately infecting healthy
volunteers with a pathogen raise important ethical issues, including the need to ensure that …