Recognition molecules and neurotrophins play important roles during development and
maintenance of nervous system functions. In this study, we provide evidence that the neural …

Synapse formation, stabilization and maintenance comprise several remarkably precise and
rapid stages. The initial steps involve delivery to the site of initial contact between axon and …

Polysialic acid (PSA) is a homopolymeric glycan that plays crucial roles in the developing
and adult nervous system. So far only a few PSA-binding proteins have been identified …

Cell adhesion molecules of the immunoglobulin (Ig) superfamily represent the biggest group
of cell adhesion molecules. They have been analyzed since approximately 40 years ago …

Cell adhesion molecules and downstream growth factor-dependent signaling are critical for
brain development and synaptic plasticity, and they have been linked to cognitive function in …

The activation of synaptic N-methyl-d-aspartate-receptors (NMDARs) is crucial for induction
of synaptic plasticity and supports cell survival, whereas activation of extrasynaptic NMDARs …

Cell adhesion molecules have been implicated in neural development and hippocampal
synaptic plasticity. Here, we investigated the role of the neural cell adhesion molecule L1 in …

Background: Alzheimer's disease (AD) is the most common form of dementia and is
characterized by a substantial reduction of neuroplasticity. Our previous work demonstrated …

Cytoplasmic dynein is well characterized as an organelle motor, but dynein also acts to
tether and stabilize dynamic microtubule plus-ends in vitro. Here we identify a novel and …

Synapse formation is mediated by a surprisingly large number and wide variety of genes
encoding many different protein classes. One of the families increasingly implicated in …