[HTML][HTML] Role of WTAP in cancer: from mechanisms to the therapeutic potential
Y Fan, X Li, H Sun, Z Gao, Z Zhu, K Yuan - Biomolecules, 2022 - mdpi.com
Wilms' tumor 1-associating protein (WTAP) is required for N6-methyladenosine (m6A) RNA
methylation modifications, which regulate biological processes such as RNA splicing, cell …
methylation modifications, which regulate biological processes such as RNA splicing, cell …
[HTML][HTML] Novel insights into mutual regulation between N6-methyladenosine modification and LncRNAs in tumors
N Zhang, Y Sun, Z Mei, Z He, S Gu - Cancer Cell International, 2023 - Springer
Abstract N6-methyladenosine (m6A), one of the most common RNA methylation
modifications, has emerged in recent years as a new layer of the regulatory mechanism …
modifications, has emerged in recent years as a new layer of the regulatory mechanism …
[HTML][HTML] Novel insights into the multifaceted roles of m6A-modified LncRNAs in cancers: biological functions and therapeutic applications
J Tang, J Zhang, Y Lu, J He, H Wang, B Liu, C Tu… - Biomarker research, 2023 - Springer
Abstract N6-methyladenosine (m6A) is considered as the most common and important
internal transcript modification in several diseases like type 2 diabetes, schizophrenia and …
internal transcript modification in several diseases like type 2 diabetes, schizophrenia and …
[HTML][HTML] The roles of N6-methyladenosine and its target regulatory noncoding RNAs in tumors: classification, mechanisms, and potential therapeutic implications
Z Liu, L Gao, L Cheng, G Lv, B Sun, G Wang… - … & Molecular Medicine, 2023 - nature.com
Abstract N6-methyladenosine (m6A) is one of the epigenetic modifications of RNA. The
addition of this chemical mark to RNA molecules regulates gene expression by affecting the …
addition of this chemical mark to RNA molecules regulates gene expression by affecting the …
N6-methyladenosine (m6A) modification in osteosarcoma: expression, function and interaction with noncoding RNAs–an updated review
Y Zhang, Y Xu, Y Bao, Y Luo, G Qiu, M He, J Lu, J Xu… - Epigenetics, 2023 - Taylor & Francis
Osteosarcoma, originating from primitive bone-forming mesenchymal cells, is the most
common malignant bone tumour among children and adolescents. N6-methyladenosine …
common malignant bone tumour among children and adolescents. N6-methyladenosine …
[HTML][HTML] New understandings of the genetic regulatory relationship between non-coding RNAs and m6A modification
S Liu, D Xiang - Frontiers in Genetics, 2023 - frontiersin.org
One of the most frequent epigenetic modifications of RNA in eukaryotes is N6
methyladenosine (m6A), which is mostly present in messenger RNAs. Through the influence …
methyladenosine (m6A), which is mostly present in messenger RNAs. Through the influence …
N6-methyladenosine reader YTHDF3 contributes to the aerobic glycolysis of osteosarcoma through stabilizing PGK1 stability
D Liu, Z Li, K Zhang, D Lu, D Zhou, Y Meng - Journal of Cancer Research …, 2023 - Springer
Abstract Purpose N6-methyladenosine (m6A) modification is a pivotal transcript chemical
modification of eukaryotics, which has been identified to play critical roles on tumor …
modification of eukaryotics, which has been identified to play critical roles on tumor …
Recent advances in the reciprocal regulation of m6A modification with non-coding RNAs and its therapeutic application in acute myeloid leukemia
J Yang, F Liang, F Zhang, H Zhao, Q Gong… - Pharmacology & …, 2024 - Elsevier
Abstract N 6-methyladenosine (m 6 A) is one of the most common modifications of RNA in
eukaryotic cells and is involved in mRNA metabolism, including stability, translation …
eukaryotic cells and is involved in mRNA metabolism, including stability, translation …
[HTML][HTML] Emerging role of RNA modification and long noncoding RNA interaction in cancer
L Yang, L Tang, Q Min, H Tian, L Li, Y Zhao… - Cancer Gene …, 2024 - nature.com
RNA modification, especially N6-methyladenosine, 5-methylcytosine, and N7-
methylguanosine methylation, participates in the occurrence and progression of cancer …
methylguanosine methylation, participates in the occurrence and progression of cancer …
[HTML][HTML] Recent advances of m6A methylation in skeletal system disease
J Liang, Q Yi, Y Liu, J Li, Z Yang, W Sun… - Journal of Translational …, 2024 - Springer
Skeletal system disease (SSD) is defined as a class of chronic disorders of skeletal system
with poor prognosis and causes heavy economic burden. m6A, methylation at the N6 …
with poor prognosis and causes heavy economic burden. m6A, methylation at the N6 …