Apoptotic signaling clears engineered Salmonella in an organ-specific manner

TJ Abele, ZP Billman, L Li, CK Harvest, AK Bryan… - Elife, 2023 - elifesciences.org
Pyroptosis and apoptosis are two forms of regulated cell death that can defend against
intracellular infection. When a cell fails to complete pyroptosis, backup pathways will initiate …

SHIP1 inhibition via 3-alpha-amino-cholestane enhances protection against Leishmania infection

BP Chowdhury, S Das, N Bodhale, SP Pandey… - Cytokine, 2023 - Elsevier
Leishmania major and L. donovani cause cutaneous leishmaniasis and visceral
leishmaniasis, respectively. Available chemotherapies suffer from toxicity, drug-resistance or …

High Selectivity of 8-Hydroxyquinoline on Leishmania (Leishmania) and Leishmania (Viannia) Species Correlates with a Potent Therapeutic Activity In Vivo

SKS Lima, JA Jesus, C Raminelli, MD Laurenti… - Pharmaceuticals, 2023 - mdpi.com
Leishmaniasis is a neglected disease caused by protozoa of the genus Leishmania, which
causes different clinical manifestations. Drugs currently used in the treatment such as …