[HTML][HTML] Flavonoids against the SARS-CoV-2 induced inflammatory storm

A Liskova, M Samec, L Koklesova, SM Samuel… - Biomedicine & …, 2021 - Elsevier
The disease severity of COVID-19, especially in the elderly and patients with co-morbidities,
is characterized by hypercytokinemia, an exaggerated immune response associated with an …

SARS-CoV-2 causes a different cytokine response compared to other cytokine storm-causing respiratory viruses in severely ill patients

M Olbei, I Hautefort, D Modos, A Treveil… - Frontiers in …, 2021 - frontiersin.org
Hyper-induction of pro-inflammatory cytokines, also known as a cytokine storm or cytokine
release syndrome (CRS), is one of the key aspects of the currently ongoing SARS-CoV-2 …

Calming the storm: natural immunosuppressants as adjuvants to target the cytokine storm in COVID-19

AE Peter, BV Sandeep, BG Rao… - Frontiers in …, 2021 - frontiersin.org
The COVID-19 pandemic has caused a global health crisis, with no specific antiviral to treat
the infection and the absence of a suitable vaccine to prevent it. While some individuals …

Role of CCL2/CCR2 axis in the pathogenesis of COVID-19 and possible Treatments: All options on the Table

M Ranjbar, A Rahimi, Z Baghernejadan… - International …, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is cause of the novel
coronavirus disease (COVID-19). In the last two years, SARS-CoV-2 has infected millions of …

A comprehensive review about immune responses and exhaustion during coronavirus disease (COVID-19)

RN Mohammed, R Tamjidifar, HS Rahman… - Cell Communication and …, 2022 - Springer
Abstract Coronavirus disease (COVID-19) is a viral infectious disease caused by the severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. The infection was reported in …

Coronavirus disease of 2019: a mimicker of dengue infection?

J Henrina, ICS Putra, S Lawrensia… - SN Comprehensive …, 2020 - Springer
At the beginning of 2020, the national health system and medical communities are faced
with unprecedented public health challenges. A novel strain of coronavirus, later identified …

COVID-19 in the elderly people and advances in vaccination approaches

K Dhama, SK Patel, S Natesan, KS Vora… - Human vaccines & …, 2020 - Taylor & Francis
The rapid worldwide spread of the COVID-19 pandemic, caused by the newly emerged
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in tens of …

COVID‐19 therapy with mesenchymal stromal cells (MSC) and convalescent plasma must consider exosome involvement: Do the exosomes in convalescent plasma …

PW Askenase - Journal of Extracellular Vesicles, 2020 - Wiley Online Library
Exosome extracellular vesicles as biologic therapy for COVID‐19 are discussed for two
areas. The first involves the growing use of mesenchymal stromal cells (MSCs) for the …

An important call: Suggestion of using IL-10 as therapeutic agent for COVID-19 with ARDS and other complications

LJ Shih, CC Yang, MT Liao, KC Lu, WC Hu, CP Lin - Virulence, 2023 - Taylor & Francis
The global coronavirus disease 2019 (COVID-19) pandemic has a detrimental impact on
public health. COVID-19 usually manifests as pneumonia, which can progress into acute …

[HTML][HTML] Fighting cytokine storm and immunomodulatory deficiency: By using natural products therapy up to now

MA Mohammed - Frontiers in Pharmacology, 2023 - frontiersin.org
A novel coronavirus strain (COVID-19) caused severe illness and mortality worldwide from
31 December 2019 to 21 March 2023. As of this writing, 761,071,826 million cases have …