Current role of SLGT2 inhibitors in the management of the whole spectrum of heart failure: focus on dapagliflozin

C Escobar, D Pascual-Figal, L Manzano… - Journal of Clinical …, 2023 - mdpi.com
Heart failure (HF) is associated with a high morbidity and mortality burden. In light of more
recent evidence, SGLT2 inhibitors are currently recommended as first-line therapy in …

Effect of SGLT2 inhibitors on heart failure outcomes and cardiovascular death across the cardiometabolic disease spectrum: a systematic review and meta-analysis

MS Usman, DL Bhatt, I Hameed, SD Anker… - The Lancet Diabetes & …, 2024 - thelancet.com
Background Sodium–glucose co-transporter-2 (SGLT2) inhibitors have been studied in
patients with heart failure, type 2 diabetes, chronic kidney disease, atherosclerotic …

Sodium-glucose cotransporter 2 inhibitor dapagliflozin prevents ejection fraction reduction, reduces myocardial and renal NF-κB expression and systemic pro …

V Quagliariello, ML Canale, I Bisceglia… - Frontiers in …, 2024 - frontiersin.org
Background Anthracycline-mediated adverse cardiovascular events are among the leading
causes of morbidity and mortality in patients with cancer. Sodium-glucose cotransporter 2 …

Ertugliflozin and hospitalization for heart failure across the spectrum of pre-trial ejection fraction: post-hoc analyses of the VERTIS CV trial

A Pandey, AA Kolkailah, F Cosentino… - European heart …, 2023 - academic.oup.com
Ertugliflozin and hospitalization for heart failure across the spectrum of pre-trial ejection fraction:
post-hoc analyses of the Page 1 Ertugliflozin and hospitalization for heart failure across the …

Recurrent heart failure hospitalizations in heart failure with preserved ejection fraction: an analysis of TOPCAT trial

Q Wang, F Yu, H Su, Z Liu, K Hu, G Wu, J Yan… - ESC Heart …, 2024 - Wiley Online Library
Aims Recurrent heart failure hospitalization (HFH) is an important feature of the progression
of heart failure (HF). In the Treatment of Preserved Cardiac Function Heart Failure with an …

Worsening heart failure: a concept in evolution

M Puthenpura, J Wilcox, WHW Tang - Current Opinion in …, 2024 - journals.lww.com
Conclusions WHF is an emerging entity within HF that defines itself as a unique point of
interest. Understanding it as a clinical measure of where a patient's HF is evolving allows for …

[HTML][HTML] Management Considerations for the Older Adult With Inflammatory Bowel Disease

E Axenfeld, S Katz, AS Faye - Gastroenterology & Hepatology, 2023 - ncbi.nlm.nih.gov
As the prevalence of older adults with inflammatory bowel disease (IBD) is rising,
understanding the unique challenges in both diagnosis and management is becoming …

[HTML][HTML] Pharmacological and Non-Pharmacological Advancements in Heart Failure Treatment

C Wang, G Fu, X Wang, N Li - Reviews in Cardiovascular Medicine, 2024 - ncbi.nlm.nih.gov
Heart failure (HF) is a complex, life-threatening condition characterized by high mortality,
morbidity, and poor quality of life. Despite studies of epidemiology, pathogenesis, and …

SGLT2 inhibition in addition to lifestyle intervention and risk for complications in subtypes of patients with prediabetes-a randomized, placebo controlled, multi-center …

R Jumpertz von Schwartzenberg, N Stefan, R Wagner… - medRxiv, 2023 - medrxiv.org
Introduction Type 2 diabetes (T2D) is associated with severe complications, including
chronic kidney disease (CKD), cardiovascular disease, heart failure and premature death …

JAMA Cardiology—The Year in Review, 2023

RO Bonow - JAMA cardiology, 2024 - jamanetwork.com
2022). Our weekly content of original research, review articles, and opinion pieces covered
the breadth of cardiology. The continuous flow of manuscripts submitted to our journal for the …