Long noncoding RNA (lncRNA)-mediated competing endogenous RNA networks provide novel potential biomarkers and therapeutic targets for colorectal cancer
Colorectal cancer (CRC) is the third most common cancer and has a high metastasis and
reoccurrence rate. Long noncoding RNAs (lncRNAs) play an important role in CRC growth …
reoccurrence rate. Long noncoding RNAs (lncRNAs) play an important role in CRC growth …
Recent updates on mechanisms of resistance to 5-fluorouracil and reversal strategies in colon cancer treatment
S Azwar, HF Seow, M Abdullah, M Faisal Jabar… - Biology, 2021 - mdpi.com
Simple Summary Acquired resistance to chemotherapy by cancer cells is the predominant
factor in chemotherapy failure, which ultimately leads to disease progression and death …
factor in chemotherapy failure, which ultimately leads to disease progression and death …
LncRNA–FEZF1-AS1 promotes tumor proliferation and metastasis in colorectal cancer by regulating PKM2 signaling
Z Bian, J Zhang, M Li, Y Feng, X Wang, J Zhang… - Clinical Cancer …, 2018 - AACR
Abstract Purpose: Long non-coding RNAs (lncRNAs) play key roles in human cancers. Here,
FEZF1-AS1, a highly overexpressed lncRNA in colorectal cancer, was identified by lncRNA …
FEZF1-AS1, a highly overexpressed lncRNA in colorectal cancer, was identified by lncRNA …
5-Fluorouracil: a narrative review on the role of regulatory mechanisms in driving resistance to this chemotherapeutic agent
5-fluorouracil (5-FU) is among the mostly administrated chemotherapeutic agents for a wide
variety of neoplasms. Non-coding RNAs have a central impact on the determination of the …
variety of neoplasms. Non-coding RNAs have a central impact on the determination of the …
Long noncoding RNA DLGAP1-AS2 promotes tumorigenesis and metastasis by regulating the Trim21/ELOA/LHPP axis in colorectal cancer
X Wang, H Cheng, J Zhao, J Li, Y Chen, K Cui, L Tian… - Molecular Cancer, 2022 - Springer
Abstract Background Long noncoding RNAs (lncRNAs) have driven research focused on
their effects as oncogenes or tumor suppressors involved in carcinogenesis. However, the …
their effects as oncogenes or tumor suppressors involved in carcinogenesis. However, the …
LncRNA signature in colorectal cancer
Colorectal cancer (CRC) is among the most frequent cancers and is associated with high
mortality particularly when being diagnosed in advanced stages. Although several …
mortality particularly when being diagnosed in advanced stages. Although several …
The potential relevance of long non-coding RNAs in colorectal cancer pathogenesis and treatment: A review focus on signaling pathways
Colorectal cancer (CRC) is one of the most frequent cancers in incidence and mortality.
Despite advances in cancer biology, molecular genetics, and targeted treatments, CRC …
Despite advances in cancer biology, molecular genetics, and targeted treatments, CRC …
SNHG17 promotes colorectal tumorigenesis and metastasis via regulating Trim23-PES1 axis and miR-339-5p-FOSL2-SNHG17 positive feedback loop
Background Small nucleolar RNA host gene (SNHG) long noncoding RNAs (lncRNAs) are
frequently dysregulated in human cancers and involved in tumorigenesis and progression …
frequently dysregulated in human cancers and involved in tumorigenesis and progression …
Non-coding RNAs targeting notch signaling pathway in cancer: From proliferation to cancer therapy resistance
M Hashemi, S Hasani, S Hajimazdarany… - International journal of …, 2022 - Elsevier
Cancer is a challenging to treat disease with a high mortality rate worldwide, nevertheless
advances in science has led to a decrease in the number of death cases caused by cancer …
advances in science has led to a decrease in the number of death cases caused by cancer …
LncRNA AFAP1-AS1 supresses miR-139-5p and promotes cell proliferation and chemotherapy resistance of non-small cell lung cancer by competitively upregulating …
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death
worldwide. This study aims to understand the underlying mechanism of lncRNA, actin …
worldwide. This study aims to understand the underlying mechanism of lncRNA, actin …