Biochemical systems theory (BST) is the foundation for a set of analytical andmodeling tools
that facilitate the analysis of dynamic biological systems. This paper depicts major …

Glioblastoma (GB) is the most common primary malignant brain tumor, and despite the
availability of chemotherapy and radiotherapy to combat the disease, overall survival …

La batalla contra el cáncer ha avanzado enormemente en los últimos treinta años y la tasa
de supervivencia se ha duplicado, sin embargo aún es difícil alcanzar una cura …

Marketed drugs frequently perform worse in clinical practice than in the clinical trials on
which their approval is based. Many therapeutic compounds are ineffective for a large …

Melanoma is a type of cancer with a relatively poor prognosis. The development of
immunotherapy for the treatment of patients with melanoma has drawn considerable …

The incidence of renal cell carcinoma (RCC) is increasing and outcomes remain poor. One-
third of patients with localized disease will relapse, and 5-year survival for patients with …

The post‐genomic era promises to pave the way to a personalized understanding of disease
processes, with technological and analytical advances helping to solve some of the world's …

Rationale Lung function measures are heritable traits that predict population morbidity and
mortality and are essential for the diagnosis of chronic obstructive pulmonary disease …

Cancer remains a fundamental burden to public health despite substantial efforts aimed at
developing effective chemotherapeutics and significant advances in chemotherapeutic …

Combining multiple types of genomic, transcriptional, proteomic, and epigenetic datasets
has the potential to reveal biological mechanisms across multiple scales, and may lead to …