[HTML][HTML] Natural killer cells in SARS-CoV-2 infection: pathophysiology and therapeutic implications

C Di Vito, F Calcaterra, N Coianiz, S Terzoli… - Frontiers in …, 2022 - frontiersin.org
Natural Killer (NK) cells are lymphocytes of the innate immunity that play a crucial role in the
control of viral infections in the absence of a prior antigen sensitization. Indeed, they display …

[HTML][HTML] The role of CD4+ FoxP3+ regulatory T cells in the immunopathogenesis of COVID-19: implications for treatment

Y Wang, J Zheng, MS Islam, Y Yang… - International journal of …, 2021 - ncbi.nlm.nih.gov
The severe cases of Coronavirus Disease 2019 (COVID-19) frequently exhibit excessive
inflammatory responses, acute respiratory distress syndrome (ARDS), coagulopathy, and …

Long-term perturbation of the peripheral immune system months after SARS-CoV-2 infection

FJ Ryan, CM Hope, MG Masavuli, MA Lynn… - BMC medicine, 2022 - Springer
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly
infectious respiratory virus which is responsible for the coronavirus disease 2019 (COVID …

Remodeling of T cell dynamics during long COVID is dependent on severity of SARS-CoV-2 infection

M Wiech, P Chroscicki, J Swatler, D Stepnik… - Frontiers in …, 2022 - frontiersin.org
Several COVID-19 convalescents suffer from the post-acute COVID-syndrome (PACS)/long
COVID, with symptoms that include fatigue, dyspnea, pulmonary fibrosis, cognitive …

Association of HLA class I genotypes with severity of coronavirus disease-19

M Shkurnikov, S Nersisyan, T Jankevic… - Frontiers in …, 2021 - frontiersin.org
Human leukocyte antigen (HLA) class I molecules play a crucial role in the development of a
specific immune response to viral infections by presenting viral peptides at the cell surface …

Neutralization of SARS‐CoV‐2 requires antibodies against conformational receptor‐binding domain epitopes

P Gattinger, K Niespodziana, K Stiasny, S Sahanic… - Allergy, 2022 - Wiley Online Library
Background The determinants of successful humoral immune response to the severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) are of critical importance for the design …

Immunologic phenotype of patients with long-COVID syndrome of 1-year duration

J García-Abellán, M Fernández, S Padilla… - Frontiers in …, 2022 - frontiersin.org
Background The pathophysiology of long-COVID remains unknown, and information is
particularly limited for symptoms of very long duration. We aimed to assess the serological, T …

SARS-CoV-2-mRNA booster vaccination reverses non-responsiveness and early antibody waning in immunocompromised patients–a phase four study comparing …

A Wagner, E Garner-Spitzer, AM Schötta… - Frontiers in …, 2022 - frontiersin.org
Background Individuals with secondary immunodeficiencies belong to the most vulnerable
groups to succumb to COVID-19 and thus are prioritized for SARS-CoV-2 vaccination …

Regulatory T cells (Tregs) and COVID-19: unveiling the mechanisms, and therapeutic potentialities with a special focus on long COVID

M Dhawan, AA Rabaan, S Alwarthan, M Alhajri… - Vaccines, 2023 - mdpi.com
The COVID-19 pandemic has caused havoc all around the world. The causative agent of
COVID-19 is the novel form of the coronavirus (CoV) named SARS-CoV-2, which results in …

A scoping review of regulatory T cell dynamics in convalescent COVID-19 patients–indications for their potential involvement in the development of Long COVID?

S Haunhorst, W Bloch, F Javelle, K Krüger… - Frontiers in …, 2022 - frontiersin.org
Background Recovery from coronavirus disease 2019 (COVID-19) can be impaired by the
persistence of symptoms or new-onset health complications, commonly referred to as Long …