The last 40 years have witnessed how p53 rose from a viral binding protein to a central
factor in both stress responses and tumor suppression. The exquisite regulation of p53 …

The formation of adipocytes during embryogenesis has been largely understudied.
However, preadipocytes appear to originate from multipotent mesenchymal stromal/stem …

Epigenetic modifications of chromatin play a critical role in regulating the fidelity of the
genetic code and in controlling the translation of genetic information into the protein …

During ripening, fleshy fruits undergo irreversible changes in color, texture, sugar content,
aroma, and flavor to appeal to seed-dispersal vectors. The onset of climacteric fruit ripening …

Fibrosis usually results from dysregulated wound repair and is characterized by excessive
scar tissue. It is a complex process with unclear mechanisms. Accumulating evidence …

The forkhead box O transcription factors convert a variety of external stimuli, including
growth factors, nutrients, and oxidative stress, into diverse biological responses through …

Many mammalian genes are transcribed during short bursts of variable frequencies and
sizes that substantially contribute to cell-to-cell variability. However, which molecular …

Abstract β‐catenin‐mediated Wnt signaling is an ancient cell‐communication pathway in
which β‐catenin drives the expression of certain genes as a consequence of the trigger …

The disruption of the gut microbial composition, defined as dysbiosis, has been associated
with many neurological disorders with inflammatory components. The alteration of the gut …

Genetic variations along with epigenetic modifications of DNA are involved in colorectal
cancer (CRC) development and progression. CRC is the fourth leading cause of cancer …