[HTML][HTML] Exploring the potential of propanamide-sulfonamide based drug conjugates as dual inhibitors of urease and cyclooxygenase-2: biological and their in silico …
Derivative synthesis has been a crucial method for altering the effects of already-approved
medications, especially to lessen adverse effects and enhance results. Making use of this …
medications, especially to lessen adverse effects and enhance results. Making use of this …
Acetylsalicylic acid-sulfa drugs conjugates as potential urease inhibitors and anti-inflammatory agents: bio-oriented drug synthesis, molecular docking, and dynamics …
S Ahmad, M Abdul Qadir, M Ahmed… - Journal of …, 2023 - Taylor & Francis
To explore the new mode of action and reduce side effects, making conjugates of existing
drugs is becoming an attractive tool in the realm of medicinal chemistry. In this work, we …
drugs is becoming an attractive tool in the realm of medicinal chemistry. In this work, we …
Recent Advancements in Refashioning of NSAIDs and their Derivatives as Anticancer Candidates
Inflammation is critical to the formation and development of tumors and is closely associated
with cancer. Therefore, addressing inflammation and the mediators that contribute to the …
with cancer. Therefore, addressing inflammation and the mediators that contribute to the …
Synthesis, Binding and Docking Studies of Indole‐1, 3, 4‐Thiadiazole Derivatives As Potent Α‐Amylase and Lox Inhibitors
MA Doddagaddavalli, U Katrahalli, SD Joshi… - …, 2024 - Wiley Online Library
Abstract Series of indole‐1, 3, 4‐thiadiazole compounds (IT 1–7) were synthesized and
characterized by FT‐IR, 1H NMR, 13C NMR and ESI‐MS spectral data. Further, the …
characterized by FT‐IR, 1H NMR, 13C NMR and ESI‐MS spectral data. Further, the …