Incidence and risk factors of drug‐induced liver injury

X Li, J Tang, Y Mao - Liver International, 2022 - Wiley Online Library
The epidemiology and aetiology of drug‐induced liver injury (DILI) vary across different
countries and populations. Overall, DILI is rare in the general population but has become …

The evolving profile of idiosyncratic drug-induced liver injury

RJ Fontana, ES Bjornsson, R Reddy… - Clinical Gastroenterology …, 2023 - Elsevier
Idiosyncratic drug-induced liver injury (DILI) is an infrequent but important cause of liver
disease. Newly identified causes of DILI include the COVID vaccines, turmeric, green tea …

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

RJ Fontana, I Liou, A Reuben, A Suzuki, MI Fiel… - Hepatology, 2023 - journals.lww.com
There are currently more than 1000 prescription medications available for use in the United
States and more than 100,000 over-the-counter herbal and dietary supplements (HDS) …

Drug-induced hypersensitivity syndrome (DIHS)/drug reaction with eosinophilia and systemic symptoms (DRESS): clinical features and pathogenesis

N Hama, R Abe, A Gibson, EJ Phillips - The Journal of Allergy and Clinical …, 2022 - Elsevier
Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic
symptoms (DIHS/DRESS) is one example of a severe delayed T-cell–mediated adverse …

ACG clinical guideline: diagnosis and management of idiosyncratic drug-induced liver injury

NP Chalasani, H Maddur, MW Russo… - Official journal of the …, 2021 - journals.lww.com
Idiosyncratic drug-induced liver injury (DILI) is common in gastroenterology and hepatology
practices, and it can have multiple presentations, ranging from asymptomatic elevations in …

Liver injury associated with turmeric—a growing problem: ten cases from the Drug-Induced Liver Injury Network [DILIN]

D Halegoua-DeMarzio, V Navarro, J Ahmad… - The American journal of …, 2023 - Elsevier
Background Turmeric is a commonly used herbal product that has been implicated in
causing liver injury. The aim of this case series is to describe the clinical, histologic, and …

Tea consumption and attenuation of biological aging: a longitudinal analysis from two cohort studies

Y Xiang, H Xu, H Chen, D Tang, Z Huang… - The Lancet Regional …, 2024 - thelancet.com
Background The biological aging process can be modified through lifestyle interventions to
prevent age-related diseases and extend healthspan. However, evidence from population …

Hepatotoxicity due to herbal dietary supplements: Past, present and the future

BJ Gurley, MR McGill, I Koturbash - Food and Chemical Toxicology, 2022 - Elsevier
Dietary supplements (DS) constitute a widely used group of products comprising vitamin,
mineral, and botanical extract formulations. DS of botanical or herbal origins (HDS) …

Clinical features, outcomes, and HLA risk factors associated with nitrofurantoin-induced liver injury

N Chalasani, YJ Li, A Dellinger, V Navarro… - Journal of …, 2023 - Elsevier
Background & Aims Nitrofurantoin (NTF) is widely used for the treatment (short-term) and
prevention (long-term) of urinary tract infections. We aimed to describe the clinical …

Challenges and future of drug-induced liver injury research—laboratory tests

S Weber, AL Gerbes - International Journal of Molecular Sciences, 2022 - mdpi.com
Drug-induced liver injury (DILI) is a rare but potentially severe adverse drug event, which is
also a major cause of study cessation and market withdrawal during drug development …