Pathogenic bacteria and viruses are the main causes of infectious diseases all over the
world. Early diagnosis of such infectious diseases is a critical step in management of their …

Infectious diseases pose serious threats to public health worldwide. Conventional diagnostic
methods for infectious diseases often exhibit low sensitivity, invasiveness, and long …

Aims The use of metagenomics for pathogen identification in clinical practice has been
limited. Here we describe a workflow to encourage the clinical utility and potential of NGS for …

Early diagnosis of pulmonary tuberculosis (PTB) is pivotal for achieving effective
tuberculosis (TB) control. This study aimed to assess the effectiveness of nanopore …

Aim: This study aimed to assess the ultra-fast method using MinION™ sequencing for rapid
identification of β-lactamase-producing Klebsiella pneumoniae clinical isolates from positive …

Purpose Bone and joint tuberculosis (BJTB) is a distinct variant of tuberculosis in which
clinical diagnosis often leads to relative misdiagnosis and missed diagnoses. This study …

Antibiotic dose optimisation in the critically ill: targets, evidence and future strategies Page 1
MCC 300512 CURRENT OPINION Antibiotic dose optimisation in the critically ill: targets …

Acute febrile illness (AFI) and severe neurological disorders (SNDs) often present diagnostic
challenges due to their potential origins from a wide range of infectious agents. Nanopore …

Background The clinical presentation of extrapulmonary tuberculosis (EPTB) is atypical and
it is easily confused with other diseases such as common infections, making prompt …

BACKGROUND Infectious diseases are still one of the greatest threats to human health, and
the etiology of 20% of cases of clinical fever is unknown; therefore, rapid identification of …