The microbiome–gut–brain axis in Parkinson disease—from basic research to the clinic

AH Tan, SY Lim, AE Lang - Nature Reviews Neurology, 2022 - nature.com
Evidence for a close bidirectional link between the brain and the gut has led to a paradigm
shift in neurology, especially in the case of Parkinson disease (PD), in which gastrointestinal …

Intestinal barrier in human health and disease

N Di Tommaso, A Gasbarrini, FR Ponziani - International journal of …, 2021 - mdpi.com
The intestinal mucosa provides a selective permeable barrier for nutrient absorption and
protection from external factors. It consists of epithelial cells, immune cells and their …

The microbiota–gut–brain Axis in psychiatric disorders

A Góralczyk-Bińkowska, D Szmajda-Krygier… - International journal of …, 2022 - mdpi.com
Modulating the gut microbiome and its influence on human health is the subject of intense
research. The gut microbiota could be associated not only with gastroenterological diseases …

High-fat, western-style diet, systemic inflammation, and gut microbiota: a narrative review

IJ Malesza, M Malesza, J Walkowiak, N Mussin… - Cells, 2021 - mdpi.com
The gut microbiota is responsible for recovering energy from food, providing hosts with
vitamins, and providing a barrier function against exogenous pathogens. In addition, it is …

Weaning stress and intestinal health of piglets: A review

X Tang, K Xiong, R Fang, M Li - Frontiers in immunology, 2022 - frontiersin.org
Weaning is considered to be one of the most critical periods in pig production, which is
related to the economic benefits of pig farms. However, in actual production, many piglets …

Gut microbiota and intestinal trans-epithelial permeability

B Allam-Ndoul, S Castonguay-Paradis… - International journal of …, 2020 - mdpi.com
Constant remodeling of tight junctions to regulate trans-epithelial permeability is essential in
maintaining intestinal barrier functions and thus preventing diffusion of small molecules and …

Alcohol, liver disease and the gut microbiota

JS Bajaj - Nature Reviews Gastroenterology & Hepatology, 2019 - nature.com
Alcoholic liver disease, which ranges from mild disease to alcoholic hepatitis and cirrhosis,
is a leading cause of morbidity and mortality worldwide. Alcohol intake can lead to changes …

[HTML][HTML] Oral delivery of proteins and peptides: Challenges, status quo and future perspectives

Q Zhu, Z Chen, PK Paul, Y Lu, W Wu, J Qi - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Proteins and peptides (PPs) have gradually become more attractive therapeutic molecules
than small molecular drugs due to their high selectivity and efficacy, but fewer side effects …

[HTML][HTML] Functions of gut microbiota metabolites, current status and future perspectives

J Liu, Y Tan, H Cheng, D Zhang, W Feng… - Aging and …, 2022 - ncbi.nlm.nih.gov
Gut microbiota, a collection of microorganisms that live within gastrointestinal tract, provides
crucial signaling metabolites for the physiological of hosts. In healthy state, gut microbiota …

Microplastic contamination of seafood intended for human consumption: a systematic review and meta-analysis

E Danopoulos, LC Jenner, M Twiddy… - Environmental Health …, 2020 - ehp.niehs.nih.gov
Background: Microplastics (MPs) have contaminated all compartments of the marine
environment including biota such as seafood; ingestion from such sources is one of the two …