[HTML][HTML] Withania somnifera (L.) Dunal: opportunity for clinical repurposing in COVID-19 management

A Saggam, K Limgaokar, S Borse… - Frontiers in …, 2021 - frontiersin.org
As the COVID-19 pandemic is progressing, the therapeutic gaps in conventional
management have highlighted the need for the integration of traditional knowledge systems …

Problems of pathogenesis and pathogenetic therapy of COVID-19 from the perspective of the general theory of pathological systems (general pathological processes)

E Gusev, A Sarapultsev, D Hu… - International journal of …, 2021 - mdpi.com
The COVID-19 pandemic examines not only the state of actual health care but also the state
of fundamental medicine in various countries. Pro-inflammatory processes extend far …

[HTML][HTML] Withania somnifera (L.) Dunal (Ashwagandha) for the possible therapeutics and clinical management of SARS-CoV-2 infection: Plant-based drug discovery …

M Singh, K Jayant, D Singh, S Bhutani… - Frontiers in Cellular …, 2022 - frontiersin.org
COVID-19 pandemic has killed huge populations throughout the world and acts as a high-
risk factor for elderly and young immune-suppressed patients. There is a critical need to …

Antiviral effects of phytochemicals against severe acute respiratory syndrome coronavirus 2 and their mechanisms of action: A review

I Jantan, L Arshad, AW Septama… - Phytotherapy …, 2023 - Wiley Online Library
The worldwide spreading of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐
2) has posed a serious threat to health, economic, environmental, and social aspects of …

Application of humanized zebrafish model in the suppression of SARS-CoV-2 spike protein induced pathology by tri-herbal medicine coronil via cytokine modulation

A Balkrishna, SK Solleti, S Verma, A Varshney - Molecules, 2020 - mdpi.com
Zebrafish has been a reliable model system for studying human viral pathologies. SARS-
CoV-2 viral infection has become a global chaos, affecting millions of people. There is an …

Structural interactions of phytoconstituent (s) from cinnamon, bay leaf, oregano, and parsley with SARS‐CoV‐2 nucleocapsid protein: A comparative assessment for …

I Husain, R Ahmad, S Siddiqui… - Journal of Food …, 2022 - Wiley Online Library
SARS‐CoV‐2 has been responsible for causing 6,218,308 deaths globally till date and has
garnered worldwide attention. The lack of effective preventive and therapeutic drugs against …

Mechanism of action of certain medicinal plants for the treatment of asthma

K Usmani, SK Jain, S Yadav - Journal of Ethnopharmacology, 2023 - Elsevier
Ethnopharmacological relevance Asthma is often treated and prevented using the
pharmacological properties of traditional medicinal plants. These healthcare systems are …

Withania somnifera extracts induced attenuation of HIV-1: a mechanistic approach to restrict viral infection

P Jadaun, R Harshithkumar, SY Gaikwad, C Seniya… - Virology Journal, 2023 - Springer
Background Several anti-retroviral drugs are available against Human immunodeficiency
virus type-1, but have multiple adverse side effects. Hence, there is an incessant compulsion …

In vitro effect of Withania somnifera, AYUSH-64, and remdesivir on the activity of CYP-450 enzymes: Implications for possible herb−drug interactions in the …

SS Kasarla, SP Borse, Y Kumar, N Sharma… - Frontiers in …, 2022 - frontiersin.org
Ayurvedic medicines Withania somnifera Dunal (ashwagandha) and AYUSH-64 have been
used for the prevention and management of COVID-19 in India. The present study explores …

Guduchi ghanavati (Ayurveda medication) improves the perceived immunity in individuals at risk of SARS-CoV-2: A multicentred, controlled, before-and-after study

A Thakar, K Panara, H Shah, B Kalsariya… - European Journal of …, 2022 - Elsevier
Introduction During the COVID-19 pandemic in India, Ayurvedic medication (Guduchi
Ghanavati, GG) was prescribed by Ayurveda physicians for prevention and management …