Interactions between the immune system and cancer: a brief review of non-spatial mathematical models

R Eftimie, JL Bramson, DJD Earn - Bulletin of mathematical biology, 2011 - Springer
We briefly review spatially homogeneous mechanistic mathematical models describing the
interactions between a malignant tumor and the immune system. We begin with the simplest …

Mathematical models for immunology: current state of the art and future research directions

R Eftimie, JJ Gillard, DA Cantrell - Bulletin of mathematical biology, 2016 - Springer
The advances in genetics and biochemistry that have taken place over the last 10 years led
to significant advances in experimental and clinical immunology. In turn, this has led to the …

Numerical solutions and geometric attractors of a fractional model of the cancer-immune based on the Atangana-Baleanu-Caputo derivative and the reproducing …

B Maayah, OA Arqub, S Alnabulsi, H Alsulami - Chinese Journal of Physics, 2022 - Elsevier
Recently, it has become critical to attempt to recognize diseases with high death rates
around the world like infectious diseases and cancer. As a result, modeling in mathematics …

Mathematical models of cancer: when to predict novel therapies, and when not to

R Brady, H Enderling - Bulletin of mathematical biology, 2019 - Springer
The number of publications on mathematical modeling of cancer is growing at an
exponential rate, according to PubMed records, provided by the US National Library of …

Dynamic interplay between tumour, stroma and immune system can drive or prevent tumour progression

RJ Seager, C Hajal, F Spill, RD Kamm… - Convergent science …, 2017 - iopscience.iop.org
In the tumour microenvironment, cancer cells directly interact with both the immune system
and the stroma. It is firmly established that the immune system, historically believed to be a …

Optimal control to develop therapeutic strategies for metastatic castrate resistant prostate cancer

JJ Cunningham, JS Brown, RA Gatenby… - Journal of theoretical …, 2018 - Elsevier
In metastatic castrate resistant prostate cancer (mCRPC), abiraterone is conventionally
administered continuously at maximal tolerated dose until treatment failure. The majority of …

Phase I trial of “bi-shRNAifurin/GMCSF DNA/autologous tumor cell” vaccine (FANG) in advanced cancer

N Senzer, M Barve, J Kuhn, A Melnyk, P Beitsch… - Molecular Therapy, 2012 - cell.com
We performed a phase I trial of FANG vaccine, an autologous tumor-based product
incorporating a plasmid encoding granulocyte-macrophage colony-stimulating factor …

Fractional order model of immune cells influenced by cancer cells

E Ucar, N Özdemir, E Altun - Mathematical Modelling of Natural …, 2019 - mmnp-journal.org
In this paper, we study the mathematical model of interaction cancer cells and immune
system cells presented Castiglione and Piccoli. As the interaction between cancer cells and …

Mathematical modelling of growth of tumour cells with chemotherapeutic cells by using Yang–Abdel–Cattani fractional derivative operator

MN Mishra, AF Aljohani - Journal of Taibah University for Science, 2022 - Taylor & Francis
Cancer is a fatal disease for a very long time. It has its own history. Now it has become one
of the major reasons for death due to its various types. Researchers, scientists and doctors …

Dynamics of fractional-order delay differential model for tumor-immune system

FA Rihan, G Velmurugan - Chaos, Solitons & Fractals, 2020 - Elsevier
Time-delays and fractional-order play a vital role in modeling biological systems with
memory. In this paper, we propose a novel delay differential model with fractional-order for …