Targeting integrin pathways: mechanisms and advances in therapy

X Pang, X He, Z Qiu, H Zhang, R Xie, Z Liu… - … and Targeted Therapy, 2023 - nature.com
Integrins are considered the main cell-adhesion transmembrane receptors that play
multifaceted roles as extracellular matrix (ECM)-cytoskeletal linkers and transducers in …

[HTML][HTML] Benefaction of probiotics for human health: A review

RG Kerry, JK Patra, S Gouda, Y Park, HS Shin… - Journal of food and drug …, 2018 - Elsevier
Humans are a unique reservoir of heterogeneous and vivacious group of microbes, which
together forms the human-microbiome superorganism. Human gut serves as a home to over …

Mechanisms and consequences of intestinal dysbiosis

GA Weiss, T Hennet - Cellular and Molecular Life Sciences, 2017 - Springer
The composition of the gut microbiota is in constant flow under the influence of factors such
as the diet, ingested drugs, the intestinal mucosa, the immune system, and the microbiota …

Antibiotics as deep modulators of gut microbiota: between good and evil

G Ianiro, H Tilg, A Gasbarrini - Gut, 2016 - gut.bmj.com
The recent increase in our knowledge of human gut microbiota has changed our view on
antibiotics. Antibiotics are, indeed, no longer considered only beneficial, but also potentially …

[HTML][HTML] Pain regulation by gut microbiota: molecular mechanisms and therapeutic potential

R Guo, LH Chen, C Xing, T Liu - British journal of anaesthesia, 2019 - Elsevier
The relationship between gut microbiota and neurological diseases, including chronic pain,
has received increasing attention. The gut microbiome is a crucial modulator of visceral …

Female gut and genital tract microbiota-induced crosstalk and differential effects of short-chain fatty acids on immune sequelae

E Amabebe, DOC Anumba - Frontiers in Immunology, 2020 - frontiersin.org
The gut and genital tract microbiota of females represent very complex biological
ecosystems that are in continuous communication with each other. The crosstalk between …

Mechanisms of action of prebiotics and their effects on gastro-intestinal disorders in adults

MPL Guarino, A Altomare, S Emerenziani, C Di Rosa… - Nutrients, 2020 - mdpi.com
In recent years, research has focused on the use of dietary fibers and prebiotics, since many
of these polysaccharides can be metabolized by intestinal microbiota, leading to the …

ILC3 function as a double-edged sword in inflammatory bowel diseases

B Zeng, S Shi, G Ashworth, C Dong, J Liu, F Xing - Cell death & disease, 2019 - nature.com
Inflammatory bowel diseases (IBD), composed mainly of Crohn's disease (CD) and
ulcerative colitis (UC), are strongly implicated in the development of intestinal inflammation …

[HTML][HTML] Antioxidant therapy for treatment of inflammatory bowel disease: does it work?

FA Moura, KQ de Andrade, JCF Dos Santos… - Redox biology, 2015 - Elsevier
Oxidative stress (OS) is considered as one of the etiologic factors involved in several signals
and symptoms of inflammatory bowel diseases (IBD) that include diarrhea, toxic megacolon …

Alcohol or gut microbiota: who is the guilty?

M Meroni, M Longo, P Dongiovanni - International journal of molecular …, 2019 - mdpi.com
Alcoholic liver disease (ALD), a disorder caused by excessive alcohol intake represents a
global health care burden. ALD encompasses a broad spectrum of hepatic injuries including …