Background Alzheimer's disease (AD) is the most frequently occurring type of dementia.
Concurrently, inadequate sleep has been recognized as a public health epidemic. Notably …

Background The association between body mass index (BMI) and Alzheimer's disease (AD)
remains controversial. Genetic and environmental factors are now considered contributors to …

Objective Androgens have been hypothesized to be involved in the pathophysiology of
cluster headache due to the male predominance, but whether androgens are altered in …

Statins are widely used for cardiovascular disease prevention but their effects on cognition
remain unclear. Statins reduce cholesterol concentration and have been suggested to …

Although the impact of sex hormones on bone metabolism is well‐documented, effect of
their primary modulator, sex hormone‐binding globulin (SHBG), remains inconclusive. This …

STUDY QUESTION Is there any methylome alteration in women with PCOS who were
diagnosed using the new international evidence-based guidelines? SUMMARY ANSWER A …

The purpose of this work was to find a link between the breast cancer (BC)-risk effects of sex
hormone-binding globulin (SHBG)-associated polymorphisms and obesity. The study was …

Genes on the X-chromosome are extensively expressed in the human brain, resulting in
substantial influences on brain development, intellectual disability, and other brain-related …

Context Chronic kidney disease (CKD) is a public health burden worldwide. Epidemiological
studies observed an association between sex hormones, including estradiol, and kidney …

In our work, the associations of GWAS (genome-wide associative studies) impact for sex-
hormone-binding globulin (SHBG)-level SNPs with the risk of breast cancer (BC) in the …