Adhesion G protein–coupled receptors (AGPCRs) are a thirty-three-member subfamily of
Class B GPCRs that control a wide array of physiological processes and are implicated in …

Tissue macrophages are a heterogeneous cell population residing in all body tissues that
contribute to the maintenance of homeostasis and trigger immune activation in response to …

The c-fms gene encodes the receptor for macrophage colony-stimulating factor (CSF-1). The
gene is expressed selectively in the macrophage and trophoblast cell lineages. Previous …

We show that the mouse macrophage-restricted F4/80 protein is not required for the
development and distribution of tissue macrophages but is involved in the generation of …

All G-protein-coupled receptors (GPCRs) share a common molecular architecture (with
seven putative transmembrane segments) and a common signaling mechanism, in that they …

Cells respond to diverse types of mechanical stimuli using a wide range of plasma
membrane-associated mechanosensitive receptors to convert extracellular mechanical cues …

Duchenne muscular dystrophy (DMD) is a progressive disease caused by the loss of
function of the protein dystrophin. This protein contributes to the stabilisation of striated cells …

Using multivalent protein probes, an evolutionarily conserved endogenous ligand for EMR2,
a human myeloid cell–restricted EGF-TM7 receptor, was identified on the surface of a …

The F4/80 monoclonal antibody was first reported in this journal 30 years ago (Eur. J.
Immunol. 1981. 11: 805–815). F4/80 has become a widely used marker for monocytes and …

The isolation of cDNA clones encoding mouse F4/80, human epidermal growth factor (EGF)
module‐containing mucin‐like hormone receptor 1 (EMR1) and human CD97 has resulted …