Potential therapeutic options for COVID-19: an update on current evidence

Z Niknam, A Jafari, A Golchin, F Danesh Pouya… - European journal of …, 2022 - Springer
Abstract SARS-CoV-2, a novel coronavirus, is the agent responsible for the COVID-19
pandemic and is a major public health concern nowadays. The rapid and global spread of …

Small molecules in the treatment of COVID-19

S Lei, X Chen, J Wu, X Duan, K Men - Signal Transduction and Targeted …, 2022 - nature.com
The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …

SARS‐COV‐2 infection and Parkinson's disease: Possible links and perspectives

HM Al‐kuraishy, AI Al‐Gareeb… - Journal of …, 2023 - Wiley Online Library
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the progressive
loss of dopaminergic neurons in the substantia nigra. The hallmarks are the presence of …

Current advances and challenges in COVID-19 vaccine development: from conventional vaccines to next-generation vaccine platforms

A Jafari, F Danesh Pouya, Z Niknam… - Molecular biology …, 2022 - Springer
The world is grappling with an unprecedented public health crisis COVID-19 pandemic
caused by the novel coronavirus SARS-CoV-2. Due to the high transmission/mortality rates …

Long COVID: clinical framing, biomarkers, and therapeutic approaches

V Conti, G Corbi, F Sabbatino, D De Pascale… - Journal of Personalized …, 2023 - mdpi.com
More than two years after the onset of the COVID-19 pandemic, healthcare providers are
facing an emergency within an emergency, the so-called long COVID or post-COVID-19 …

Cellular metabolism: a fundamental component of degeneration in the nervous system

K Maiese - Biomolecules, 2023 - mdpi.com
It is estimated that, at minimum, 500 million individuals suffer from cellular metabolic
dysfunction, such as diabetes mellitus (DM), throughout the world. Even more concerning is …

[HTML][HTML] COVID-19 and atrial fibrillation: Intercepting lines

M Donniacuo, A De Angelis, C Rafaniello… - Frontiers in …, 2023 - frontiersin.org
Almost 20% of COVID-19 patients have a history of atrial fibrillation (AF), but also a new-
onset AF represents a frequent complication in COVID-19. Clinical evidence demonstrates …

COVID-19 complications: Oxidative stress, inflammation, and mitochondrial and endothelial dysfunction

E Georgieva, J Ananiev, Y Yovchev… - International Journal of …, 2023 - mdpi.com
SARS-CoV-2 infection, discovered and isolated in Wuhan City, Hubei Province, China,
causes acute atypical respiratory symptoms and has led to profound changes in our lives …

Immune-mediated inflammatory responses of alveolar epithelial cells: Implications for COVID-19 lung pathology

A Barilli, R Visigalli, F Ferrari, MG Bianchi, V Dall'Asta… - Biomedicines, 2022 - mdpi.com
Background. Clinical and experimental evidence point to a dysregulated immune response
caused by SARS-CoV-2 as the primary mechanism of lung disease in COVID-19. However …

First recombinant high-density lipoprotein particles administration in a severe ICU COVID-19 patient, a multi-omics exploratory investigation

S Tanaka, F Begue, B Veeren, A Tran-Dinh, T Robert… - Biomedicines, 2022 - mdpi.com
High-density lipoproteins (HDLs) have multiple endothelioprotective properties. During
SARS-CoV-2 infection, HDL-cholesterol (HDL-C) concentration is markedly reduced, and …