Convergent evolution in SARS-CoV-2 spike creates a variant soup from which new COVID-19 waves emerge
The first 2 years of the COVID-19 pandemic were mainly characterized by recurrent
mutations of SARS-CoV-2 Spike protein at residues K417, L452, E484, N501 and P681 …
mutations of SARS-CoV-2 Spike protein at residues K417, L452, E484, N501 and P681 …
Vaccines and therapeutics for immunocompromised patients with COVID-19
The COVID-19 pandemic has disproportionately impacted immunocompromised patients.
This diverse group is at increased risk for impaired vaccine responses, progression to …
This diverse group is at increased risk for impaired vaccine responses, progression to …
SARS-CoV-2 variants resistant to monoclonal antibodies in immunocompromised patients constitute a public health concern
A Casadevall, D Focosi - The Journal of clinical …, 2023 - Am Soc Clin Investig
COVID-19 in immunocompromised hosts has emerged as a difficult therapeutic
management problem. Immunocompromised hosts mount weak responses to SARS-CoV-2 …
management problem. Immunocompromised hosts mount weak responses to SARS-CoV-2 …
Triple combination therapy with 2 antivirals and monoclonal antibodies for persistent or relapsed severe acute respiratory syndrome coronavirus 2 infection in …
M Mikulska, C Sepulcri, C Dentone… - Clinical Infectious …, 2023 - academic.oup.com
Background Severely immunocompromised patients are at risk for prolonged or relapsed
Coronavirus Disease 2019 (COVID-19), leading to increased morbidity and mortality. We …
Coronavirus Disease 2019 (COVID-19), leading to increased morbidity and mortality. We …
The Omicron variant of concern: Diversification and convergent evolution in spike protein, and escape from anti-Spike monoclonal antibodies
Abstract WHO-defined SARS-CoV-2 variants of concern (VOC) drive therapeutics and
vaccine development. The Omicron VOC is dominating the arena since November 2021, but …
vaccine development. The Omicron VOC is dominating the arena since November 2021, but …
Guidance on the use of convalescent plasma to treat immunocompromised patients with coronavirus disease 2019
Abstract Coronavirus disease 2019 (COVID-19) convalescent plasma (CCP) is a safe and
effective treatment for COVID-19 in immunocompromised (IC) patients. IC patients have a …
effective treatment for COVID-19 in immunocompromised (IC) patients. IC patients have a …
A systematic review and meta-analysis on the real-world effectiveness of COVID-19 vaccines against infection, symptomatic and severe COVID-19 disease caused by …
H Mohammed, DD Pham-Tran, ZYM Yeoh, B Wang… - Vaccines, 2023 - mdpi.com
Real-world data on the effectiveness of COVID-19 vaccines against the Omicron variant (B.
1.1. 529) is limited. This systematic review aimed to investigate the real-world effectiveness …
1.1. 529) is limited. This systematic review aimed to investigate the real-world effectiveness …
Plasma after both SARS-CoV-2 boosted vaccination and COVID-19 potently neutralizes BQ. 1.1 and XBB. 1
DJ Sullivan, M Franchini… - Journal of General …, 2023 - microbiologyresearch.org
Recent 2022 SARS-CoV-2 Omicron variants, have acquired resistance to most neutralizing
anti-Spike monoclonal antibodies authorized, and the BQ. 1.* sublineages are notably …
anti-Spike monoclonal antibodies authorized, and the BQ. 1.* sublineages are notably …
Convalescent plasma therapy in COVID-19: Unravelling the data using the principles of antibody therapy
A Casadevall, MJ Joyner, LA Pirofski… - Expert review of …, 2023 - Taylor & Francis
Introduction When the COVID-19 pandemic struck no specific therapies were available and
many turned to COVID-19 convalescent plasma (CCP), a form of antibody therapy. The …
many turned to COVID-19 convalescent plasma (CCP), a form of antibody therapy. The …
SARS-CoV-2 BA. 2.86 (“Pirola”): Is it Pi or Just Another Omicron Sublineage?
Vaccines | Free Full-Text | SARS-CoV-2 BA.2.86 (“Pirola”): Is it Pi or Just Another
Omicron Sublineage? Next Article in Journal / Special Issue Analysing the In-Use Stability of …
Omicron Sublineage? Next Article in Journal / Special Issue Analysing the In-Use Stability of …