Two years into the COVID-19 pandemic: lessons learned
SJR da Silva, JCF do Nascimento… - ACS infectious …, 2022 - ACS Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
and virulent human-infecting coronavirus that emerged in late December 2019 in Wuhan …
and virulent human-infecting coronavirus that emerged in late December 2019 in Wuhan …
A scoping review of the pathophysiology of COVID-19
COVID-19 is a highly heterogeneous and complex medical disorder; indeed, severe COVID-
19 is probably amongst the most complex of medical conditions known to medical science …
19 is probably amongst the most complex of medical conditions known to medical science …
Classic Signaling Pathways in Alveolar Injury and Repair Involved in Sepsis‐Induced ALI/ARDS: New Research Progress and Prospect
W Li, D Li, Y Chen, H Abudou, H Wang, J Cai… - Disease …, 2022 - Wiley Online Library
Sepsis is a common critical clinical disease with high mortality that can cause approximately
10 million deaths worldwide each year. Acute lung injury (ALI) or acute respiratory distress …
10 million deaths worldwide each year. Acute lung injury (ALI) or acute respiratory distress …
[HTML][HTML] Relation of serum copper status to survival in COVID-19
J Hackler, RA Heller, Q Sun, M Schwarzer, J Diegmann… - Nutrients, 2021 - mdpi.com
The trace element copper (Cu) is part of our nutrition and essentially needed for several
cuproenzymes that control redox status and support the immune system. In blood, the …
cuproenzymes that control redox status and support the immune system. In blood, the …
[HTML][HTML] Differential co-expression network analysis reveals key hub-high traffic genes as potential therapeutic targets for COVID-19 pandemic
Background The recent emergence of COVID-19, rapid worldwide spread, and incomplete
knowledge of molecular mechanisms underlying SARS-CoV-2 infection have limited …
knowledge of molecular mechanisms underlying SARS-CoV-2 infection have limited …
Investigating Lipid-Modulating Agents for Prevention or Treatment of COVID-19: JACC State-of-the-Art Review
AH Talasaz, P Sadeghipour… - Journal of the American …, 2021 - jacc.org
Abstract Coronavirus disease-2019 (COVID-19) is associated with systemic inflammation,
endothelial activation, and multiorgan manifestations. Lipid-modulating agents may be …
endothelial activation, and multiorgan manifestations. Lipid-modulating agents may be …
[HTML][HTML] Induction of exaggerated cytokine production in human peripheral blood mononuclear cells by a recombinant SARS-CoV-2 spike glycoprotein S1 and its …
An understanding of the pathological inflammatory mechanisms involved in SARS-CoV-2
virus infection is necessary in order to discover new molecular pharmacological targets for …
virus infection is necessary in order to discover new molecular pharmacological targets for …
[HTML][HTML] Mechanistic insights into the immune pathophysiology of COVID-19; an in-depth review
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which causes
coronavirus-19 (COVID-19), has caused significant morbidity and mortality globally. In …
coronavirus-19 (COVID-19), has caused significant morbidity and mortality globally. In …
[HTML][HTML] Regulation of inflammatory cytokine storms by mesenchymal stem cells
L Wang, Y Li, M Xu, Z Deng, Y Zhao, M Yang… - Frontiers in …, 2021 - frontiersin.org
Mesenchymal stem cells (MSCs) have been widely used in preclinical and clinical trials for
various diseases and have shown great potential in the treatment of sepsis and coronavirus …
various diseases and have shown great potential in the treatment of sepsis and coronavirus …
Vaccine design and delivery approaches for COVID-19
K Shahzamani, F Mahmoudian… - International …, 2021 - Elsevier
COVID-19 is still a deadly disease that remains yet a major challenge for humans. In recent
times, many large pharmaceutical and non-pharmaceutical companies have invested a lot of …
times, many large pharmaceutical and non-pharmaceutical companies have invested a lot of …