Unraveling the complex roles of macrophages in obese adipose tissue: an overview

C Peng, J Chen, R Wu, H Jiang, J Li - Frontiers of medicine, 2024 - Springer
Macrophages, a heterogeneous population of innate immune cells, exhibit remarkable
plasticity and play pivotal roles in coordinating immune responses and maintaining tissue …

Application of the Nicoya OpenSPR to Studies of Biomolecular Binding: A Review of the Literature from 2016 to 2022

EK Hanson, RJ Whelan - Sensors, 2023 - mdpi.com
The Nicoya OpenSPR is a benchtop surface plasmon resonance (SPR) instrument. As with
other optical biosensor instruments, it is suitable for the label-free interaction analysis of a …

Piezo1‐mediated M2 macrophage mechanotransduction enhances bone formation through secretion and activation of transforming growth factor‐β1

G Cai, Y Lu, W Zhong, T Wang, Y Li, X Ruan… - Cell …, 2023 - Wiley Online Library
Macrophages are multifunctional immune system cells that are essential for the mechanical
stimulation‐induced control of metabolism. Piezo1 is a non‐selective calcium channel …

SLC3A2 promotes tumor‐associated macrophage polarization through metabolic reprogramming in lung cancer

Z Li, S Chen, X He, S Gong, L Sun, L Weng - Cancer science, 2023 - Wiley Online Library
Tumor‐associated macrophages (TAMs) are one of the most abundant immunosuppressive
cells in the tumor microenvironment and possess crucial functions in facilitating tumor …

[HTML][HTML] Green tea derivative-based hydrogel with ROS-scavenging property for accelerating diabetic wound healing

G Jia, Z Li, H Le, Z Jiang, Y Sun, H Liu, F Chang - Materials & Design, 2023 - Elsevier
The accumulation of reactive oxygen species (ROS) in the oxidative stress
microenvironment of diabetic wounds often results in delayed wound healing. In this study, a …

Large yellow tea polysaccharides ameliorate obesity-associated metabolic syndrome by promoting M2 polarization of adipose tissue macrophages

H Wang, L Wang, H Cheng, H Ge, Z Xie, D Li - Food & Function, 2023 - pubs.rsc.org
Obesity-induced metabolic syndrome is strongly associated with infiltrated adipose tissue
macrophages (ATMs). Large yellow tea, a traditional functional beverage in China, has been …

Thermogenic adipocyte-derived zinc promotes sympathetic innervation in male mice

J Jiang, D Zhou, A Zhang, W Yu, L Du, H Yuan… - Nature …, 2023 - nature.com
Sympathetic neurons activate thermogenic adipocytes through release of catecholamine;
however, the regulation of sympathetic innervation by thermogenic adipocytes is unclear …

[HTML][HTML] Rapamycin incorporating hydrogel improves the progression of osteoarthritis by inducing synovial macrophages polarization and reducing intra-articular …

B Chen, J Wang, X Jin, X Wang, Z Fan, Y Zhang… - Materials & Design, 2023 - Elsevier
In the macrophage-specific mTORC1 signaling activation model, the synovial macrophages
polarized toward M1, thus aggravating synovitis and progression of OA. Therefore, intra …

Intervention of tanshinone IIA on the PGK1-PDHK1 pathway to reprogram macrophage phenotype after myocardial infarction

S Gao, Z Yang, D Li, B Wang, X Zheng, C Li… - … Drugs and Therapy, 2023 - Springer
Background Myocardial infarction remains a disease with high morbidity and death rate
among cardiovascular diseases. Macrophages are abundant immune cells in the heart …

Combinatorial macrophage induced innate immunotherapy against Ewing sarcoma: Turning “Two Keys” simultaneously

W Luo, H Hoang, KE Miller, H Zhu, S Xu, X Mo… - Journal of Experimental …, 2024 - Springer
Macrophages play important roles in phagocytosing tumor cells. However, tumors escape
macrophage phagocytosis in part through the expression of anti-phagocytic signals, most …