Do men die young and sick, or do women live long and healthy? By trying to explain the
sexual dimorphism in life expectancy, both biological and environmental aspects are …

Testosterone (T) is the principal male sex hormone. As men age, T levels typically fall.
Symptoms of low T include decreased libido, vasomotor instability, and decreased bone …

Background Serum testosterone concentrations decrease as men age, but benefits of
raising testosterone levels in older men have not been established. Methods We assigned …

Importance Rates of testosterone therapy are increasing and the effects of testosterone
therapy on cardiovascular outcomes and mortality are unknown. A recent randomized …

Background An association between testosterone therapy (TT) and cardiovascular disease
has been reported and TT use is increasing rapidly. Methods We conducted a cohort study …

Obesity is an emerging condition, with a prevalence of~ 20%. Although the simple
measurement of BMI is likely a simplistic approach to obesity, BMI is easily calculated, and …

A wealth of observational studies show that low testosterone is associated with insulin
resistance and with an increased risk of diabetes and the metabolic syndrome. Experimental …

Context: Middle-aged and older men (≥ 50 years), especially those who are obese and
suffer from comorbidities, not uncommonly present with clinical features consistent with …

OBJECTIVE To determine whether testosterone therapy improves glucose metabolism in
men with type 2 diabetes (T2D) and lowered testosterone. RESEARCH DESIGN AND …

Testosterone plays a central role in male development and health. Likewise, androgen
deficiency, or hypogonadism, is associated with a variety of symptoms including decreased …