SARS-CoV-2 BA. 2.86 enters lung cells and evades neutralizing antibodies with high efficiency

L Zhang, A Kempf, I Nehlmeier, A Cossmann, A Richter… - Cell, 2024 - cell.com
Summary BA. 2.86, a recently identified descendant of the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) Omicron BA. 2 sublineage, contains∼ 35 mutations …

SARS-CoV-2: an update on the biological interplay with the human host

G Lippi, F Sanchis-Gomar, C Mattiuzzi, BM Henry - COVID, 2023 - mdpi.com
Coronavirus Disease 2019 (COVID-19) is an infectious respiratory illness caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease, first identified in the …

The Ways of the Virus: Interactions of Platelets and Red Blood Cells with SARS-CoV-2, and Their Potential Pathophysiological Significance in COVID-19

MA Panteleev, AN Sveshnikova… - International Journal of …, 2023 - mdpi.com
The hematological effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) are important in COVID-19 pathophysiology. However, the interactions of SARS-CoV-2 …

Virological characteristics correlating with SARS-CoV-2 spike protein fusogenicity

MSTM Begum, K Ichihara, O Takahashi… - Frontiers in …, 2024 - frontiersin.org
Introduction The severe acute respiratory syndrome coronavirus (SARS-CoV-2) spike (S)
protein is essential in mediating membrane fusion of the virus with the target cells. Several …

[HTML][HTML] Evolving spike-protein N-glycosylation in SARS-CoV-2 variants

S Baboo, JK Diedrich, JL Torres, J Copps, B Singh… - Biorxiv, 2023 - ncbi.nlm.nih.gov
Abstract Since> 3 years, SARS-CoV-2 has plunged humans into a colossal pandemic.
Henceforth, multiple waves of infection have swept through the human population, led by …

Efficient overexpression and purification of severe acute respiratory syndrome coronavirus 2 nucleocapsid proteins in Escherichia coli

EL Brudenell, MB Pohare, D Zafred, J Phipps… - Biochemical …, 2024 - portlandpress.com
The fundamental biology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
nucleocapsid protein (Ncap), its use in diagnostic assays and its potential application as a …

[HTML][HTML] Development of a single-chain variable antibody fragment against a conserved region of the SARS-CoV-2 spike protein

T Gao, A Irie, T Kouwaki, H Oshiumi - Scientific Reports, 2024 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has prolonged the duration
of the pandemic because of the continuous emergence of new variant strains. The …

SARS-CoV-2 Omicron: Viral Evolution, Immune Evasion, and Alternative Durable Therapeutic Strategies

H Guo, S Ha, JW Botten, K Xu, N Zhang, Z An… - Viruses, 2024 - mdpi.com
Since the SARS-CoV-2 Omicron virus has gained dominance worldwide, its continual
evolution with unpredictable mutations and patterns has revoked all authorized …

Flublok Quadrivalent Vaccine Adjuvanted with R-DOTAP Elicits a Robust and Multifunctional CD4 T Cell Response That Is of Greater Magnitude and Functional …

CL White, MA Glover, SK Gandhapudi, KA Richards… - Vaccines, 2024 - mdpi.com
It is clear that new approaches are needed to promote broadly protective immunity to viral
pathogens, particularly those that are prone to mutation and escape from antibody-mediated …

Reverse mutational scanning of spike BA. 2.86 identifies the epitopes contributing to immune escape from polyclonal sera

N Bdeir, T Lüddecke, H Maaß, S Schmelz, H Jacobsen… - medRxiv, 2024 - medrxiv.org
The recently detected Omicron BA. 2.86 lineage contains more than 30 amino acid
mutations relative to BA. 2. Here, we identify the epitopes driving immune escape of BA. 2.86 …