The rapid development of 3D printing has led to considerable progress in the field of
biomedical engineering. Notably, 4D printing provides a potential strategy to achieve a time …

Malformations of cortical development are a group of rare disorders commonly manifesting
with developmental delay, cerebral palsy or seizures. The neurological outcome is …

Despite the remarkable cognitive power, humans are not alien beings living in their isolated
universe but part of the Earth's biosphere–a dynamic, intelligent system. The working of the …

Neanderthal brains were similar in size to those of modern humans. We sought to
investigate potential differences in neurogenesis during neocortex development. Modern …

Modern society faces major environmental problems, but there are many difficulties in
studying the nature–human relationship from an integral psychosocial perspective. We …

The mammalian gut harbors a complex and dynamic microbial ecosystem: the microbiota.
While emerging studies support that microbiota regulates brain function with a few molecular …

Human cognitive abilities are generally thought to arise from cortical expansion over the
course of human brain evolution. In addition to increased neuron numbers, this cortical …

Human cerebral cortex size and complexity has increased greatly during evolution. While
increased progenitor diversity and enhanced proliferative potential play important roles in …

The ability to model human brain development in vitro represents an important step in our
study of developmental processes and neurological disorders. Protocols that utilize human …

Folding of the cerebral cortex is a fundamental milestone of mammalian brain evolution and
is associated with dramatic increases in size and complexity. New animal models, genetic …