2019 WSES guidelines for the management of severe acute pancreatitis

A Leppäniemi, M Tolonen, A Tarasconi… - World journal of …, 2019 - Springer
Although most patients with acute pancreatitis have the mild form of the disease, about 20–
30% develops a severe form, often associated with single or multiple organ dysfunction …

New insights into acute pancreatitis

PJ Lee, GI Papachristou - Nature reviews Gastroenterology & …, 2019 - nature.com
The incidence of acute pancreatitis continues to increase worldwide, and it is one of the
most common gastrointestinal causes for hospital admission in the USA. In the past decade …

American Gastroenterological Association Institute guideline on initial management of acute pancreatitis

SD Crockett, S Wani, TB Gardner, Y Falck-Ytter… - …, 2018 - gastrojournal.org
(AGA) on the initial management of acute pancreatitis (AP). The guideline was developed by
the AGA's Clinical Practice Guideline Committee and approved by the AGA Governing …

Current concepts in severe acute and necrotizing pancreatitis: an evidence-based approach

G Trikudanathan, DRJ Wolbrink, HC van Santvoort… - Gastroenterology, 2019 - Elsevier
The incidence of acute pancreatitis continues to rise, inducing substantial medical and
social burden, with annual costs exceeding $2 billion in the United States alone. Although …

Guidelines for the management of patients with severe acute pancreatitis, 2021

S Jaber, M Garnier, K Asehnoune, F Bounes… - … Critical Care & Pain …, 2022 - Elsevier
Objective To provide guidelines for the management of the intensive care patient with
severe acute pancreatitis. Design A consensus committee of 22 experts was convened. A …

[HTML][HTML] NLRP3 inflammasome regulates development of systemic inflammatory response and compensatory anti-inflammatory response syndromes in mice with …

M Sendler, C van den Brandt, J Glaubitz, A Wilden… - Gastroenterology, 2020 - Elsevier
Background & Aims Pancreatitis starts with primarily sterile local inflammation that induces
systemic inflammatory response syndrome, followed by compensatory anti-inflammatory …

[HTML][HTML] Endoscopic versus surgical step-up approach for infected necrotizing pancreatitis (ExTENSION): long-term follow-up of a randomized trial

AM Onnekink, L Boxhoorn, HC Timmerhuis, ST Bac… - Gastroenterology, 2022 - Elsevier
Background & Aims Previous randomized trials, including the Transluminal Endoscopic Step-
Up Approach Versus Minimally Invasive Surgical Step-Up Approach in Patients With …

Acute pancreatitis: current perspectives on diagnosis and management

AP Shah, MM Mourad, SR Bramhall - Journal of inflammation …, 2018 - Taylor & Francis
The last two decades have seen the emergence of significant evidence that has altered
certain aspects of the management of acute pancreatitis. While most cases of acute …

Severe acute pancreatitis: surgical indications and treatment

M Heckler, T Hackert, K Hu, CM Halloran… - … archives of surgery, 2021 - Springer
Background Acute pancreatitis (AP) is defined as an acute inflammatory attack of the
pancreas of sudden onset. Around 25% of patients have either moderately severe or severe …

Wedelolactone alleviates acute pancreatitis and associated lung injury via GPX4 mediated suppression of pyroptosis and ferroptosis

R Fan, J Sui, X Dong, B Jing, Z Gao - Free Radical Biology and Medicine, 2021 - Elsevier
Acute pancreatitis (AP) is an inflammatory disorder associated with multiple organ failure.
Pyroptosis and ferroptosis are two newly recognized cell death, and whether pyroptosis and …