Trimethylamine N-oxide promotes hyperlipidemia acute pancreatitis via inflammatory response

G Yang, X Zhang - Canadian journal of physiology and …, 2022 - cdnsciencepub.com
Trimethylamine N-oxide (TMAO), a metabolite of gut microbiota, is involved in the regulation
of lipid metabolism and inflammatory response; however, the role of TMAO in hyperlipidemia …

Managing infected pancreatic necrosis

JE Thomson, SM Van Dijk, M Brand, HC Van Santvoort… - 2018 - repository.up.ac.za
The management of infected pancreatic necrosis has historically been based on early, open
necro-sectomy, associated with significant mortality. In recent years, an evidence based …

Vitamin D deficiency predicts severe acute pancreatitis

JH Huh, JW Kim, KJ Lee - United European …, 2019 - journals.sagepub.com
Background The ability to predict the severity of disease is important to reduce morbidity and
mortality in patients with acute pancreatitis (AP). Vitamin D deficiency has been associated …

[HTML][HTML] Acute pancreatitis: Current clinical approaches, molecular pathophysiology, and potential therapeutics

MB Wiley, K Mehrotra, J Bauer, C Yazici… - Pancreas, 2023 - journals.lww.com
Objective Severe acute pancreatitis (SAP), pancreatic inflammation leading to multiorgan
failure, is associated with high morbidity and mortality. There is a critical need to identify …

[HTML][HTML] Impact of comorbidities on hospital mortality in patients with acute pancreatitis: a population-based study of 110,021 patients

NJ Hidalgo, E Pando, R Mata, N Fernandes… - BMC …, 2023 - Springer
Background The impact of pre-existing comorbidities on acute pancreatitis (AP) mortality is
not clearly defined. Our study aims to determine the trend in AP hospital mortality and the …

[HTML][HTML] Dynamic blood presepsin levels are associated with severity and outcome of acute pancreatitis: A prospective cohort study

HL Xiao, GX Wang, Y Wang, ZM Tan… - World Journal of …, 2022 - ncbi.nlm.nih.gov
BACKGROUND Acute pancreatitis (AP) is an inflammatory disorder of the pancreas with an
unpredictable course of illness. A major challenge of AP is the early identification of patients …

[HTML][HTML] Plasmatic oxidative and metabonomic profile of patients with different degrees of biliary acute pancreatitis severity

P Silva-Vaz, I Jarak, L Rato, PF Oliveira… - Antioxidants, 2021 - mdpi.com
Acute pancreatitis (AP) is an inflammatory process of the pancreas with variable involvement
of the pancreatic and peripancreatic tissues and remote organ systems. The main goal of …

[HTML][HTML] A narrative review of the mechanism of acute pancreatitis and recent advances in its clinical management

Z Zheng, YX Ding, YX Qu, F Cao, F Li - American journal of …, 2021 - ncbi.nlm.nih.gov
Acute pancreatitis (AP) is a common gastrointestinal disease with a high risk of mortality.
Recently, the exosome and its potential regulatory role in the progression of AP has …

[HTML][HTML] New challenges for microRNAs in acute pancreatitis: progress and treatment

W Zhou, S Dong, Z Chen, X Li, W Jiang - Journal of Translational …, 2022 - Springer
Acute pancreatitis (AP) is a common clinical abdominal emergency, with a high and
increasing incidence each year. Severe AP can easily cause systemic inflammatory …

Circ_UTRN ameliorates caerulein-induced acute pancreatitis in vitro via reducing inflammation and promoting apoptosis through miR-320-3p/PTK2 axis

Q Sun, R Liang, M Li, H Zhou - Journal of Pharmacy and …, 2022 - academic.oup.com
Abstract Objectives Circular RNAs (circRNAs) have been demonstrated to play important
roles in acute pancreatitis (AP). Herein, this study aimed to investigate the role and …