Melanopsin photoreception contributes to human visual detection, temporal and colour processing

AJ Zele, B Feigl, P Adhikari, ML Maynard, D Cao - Scientific reports, 2018 - nature.com
The visual consequences of melanopsin photoreception in humans are not well understood.
Here we studied melanopsin photoreception using a technique of photoreceptor silent …

[HTML][HTML] Melanopsin and cone photoreceptor inputs to the afferent pupil light response

AJ Zele, P Adhikari, D Cao, B Feigl - Frontiers in neurology, 2019 - frontiersin.org
Background: Retinal photoreceptors provide the main stage in the mammalian eye for
regulating the retinal illumination through changes in pupil diameter, with a small population …

[PDF][PDF] Melanopsin photoreception differentially modulates rod-mediated and cone-mediated human temporal vision

S Uprety, P Adhikari, B Feigl, AJ Zele - Iscience, 2022 - cell.com
To evaluate the nature of interactions between visual pathways transmitting the slower
melanopsin and faster rod and cone signals, we implement a temporal phase summation …

[HTML][HTML] Protocol for isolation of melanopsin and rhodopsin in the human eye using silent substitution

TW Nugent, DD Carter, S Uprety, P Adhikari, B Feigl… - STAR protocols, 2023 - Elsevier
Melanopsin-mediated visual and non-visual functions are difficult to study in vivo. To isolate
melanopsin responses, non-standard light stimulation instruments are required, with at least …

[HTML][HTML] Melanopsin driven enhancement of cone-mediated visual processing

AJ Zele, P Adhikari, D Cao, B Feigl - Vision research, 2019 - Elsevier
The precise control of visual sensitivity to variations in external lighting is critical for
optimising human visual function in a changing environment. In photopic illumination, the …

Optimizing methods to isolate melanopsin-directed responses

S Uprety, AJ Zele, B Feigl, D Cao, P Adhikari - JOSA A, 2021 - opg.optica.org
The intrinsic melanopsin photoresponse may initiate visual signals that differ in
spatiotemporal characteristics from the cone-opsin-and rhodopsin-mediated signals …

[HTML][HTML] Light adaptation characteristics of melanopsin

M Pant, AJ Zele, B Feigl, P Adhikari - Vision Research, 2021 - Elsevier
Following photopigment bleaching, the rhodopsin and cone-opsins show a characteristic
exponential regeneration in the dark with a photocycle dependent on the retinal pigment …

[图书][B] Melanopsin vision: Sensation and perception through intrinsically photosensitive retinal ganglion cells

DS Joyce, KW Houser, SN Peirson, JM Zeitzer, AJ Zele - 2022 - cambridge.org
Intrinsically photosensitive retinal ganglion cells (ipRGCs) are the most recently discovered
photoreceptor class in the human retina. This Element integrates new knowledge and …

Melanopsin-mediated amplification of cone signals in the human visual cortex

P Adhikari, S Uprety, B Feigl… - Proceedings of the …, 2024 - royalsocietypublishing.org
The ambient daylight variation is coded by melanopsin photoreceptors and their luxotonic
activity increases towards midday when colour temperatures are cooler, and irradiances are …

[HTML][HTML] Threshold vision under full-field stimulation: Revisiting the minimum number of quanta necessary to evoke a visual sensation

A Dey, AJ Zele, B Feigl, P Adhikari - Vision Research, 2021 - Elsevier
At the absolute threshold of vision, Hecht, Shlaer and Pirenne estimate that 5–14 photons
are absorbed within a retinal area containing~ 500 rods. Other estimates of scotopic …