T cell responses to SARS-CoV-2 infection and vaccination are elevated in B cell deficiency and reduce risk of severe COVID-19
R Zonozi, LC Walters, A Shulkin, V Naranbhai… - Science translational …, 2023 - science.org
Individuals with primary and pharmacologic B cell deficiencies have high rates of severe
disease and mortality from coronavirus disease 2019 (COVID-19), but the immune …
disease and mortality from coronavirus disease 2019 (COVID-19), but the immune …
Lateral flow assays for viruses diagnosis: Up-to-date technology and future prospects
B Ince, MK Sezgintürk - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
Bacteria, viruses, and parasites are harmful microorganisms that cause infectious diseases.
Early detection of diseases is critical to prevent disease transmission and provide epidemic …
Early detection of diseases is critical to prevent disease transmission and provide epidemic …
[HTML][HTML] Therapeutic targets and interventional strategies in COVID-19: mechanisms and clinical studies
YW Zhou, Y Xie, LS Tang, D Pu, YJ Zhu… - Signal transduction and …, 2021 - nature.com
Owing to the limitations of the present efforts on drug discovery against severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and the lack of the understanding of the …
respiratory syndrome coronavirus 2 (SARS-CoV-2) and the lack of the understanding of the …
Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice
DR Martinez, A Schäfer, SR Leist, G De la Cruz, A West… - Science, 2021 - science.org
The emergence of severe acute respiratory syndrome coronavirus (SARS-CoV) in 2003 and
SARS-CoV-2 in 2019 highlights the need to develop universal vaccination strategies against …
SARS-CoV-2 in 2019 highlights the need to develop universal vaccination strategies against …
[HTML][HTML] Quick COVID-19 healers sustain anti-SARS-CoV-2 antibody production
Y Chen, A Zuiani, S Fischinger, J Mullur, C Atyeo… - Cell, 2020 - cell.com
Antibodies are key immune effectors that confer protection against pathogenic threats. The
nature and longevity of the antibody response to SARS-CoV-2 infection are not well defined …
nature and longevity of the antibody response to SARS-CoV-2 infection are not well defined …
[HTML][HTML] Molecular characteristics, immune evasion, and impact of SARS-CoV-2 variants
The persistent COVID-19 pandemic since 2020 has brought an enormous public health
burden to the global society and is accompanied by various evolution of the virus genome …
burden to the global society and is accompanied by various evolution of the virus genome …
SARS-CoV-2 antiviral therapy
The development of effective antiviral therapy for COVID-19 is critical for those awaiting
vaccination, as well as for those who do not respond robustly to vaccination. This review …
vaccination, as well as for those who do not respond robustly to vaccination. This review …
[HTML][HTML] Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape
Antibody cocktails represent a promising approach to prevent SARS-CoV-2 escape. The
determinants for selecting antibody combinations and the mechanism that antibody cocktails …
determinants for selecting antibody combinations and the mechanism that antibody cocktails …
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection
Broadly neutralizing antibodies (bnAbs) to coronaviruses (CoVs) are valuable in their own
right as prophylactic and therapeutic reagents to treat diverse CoVs and as templates for …
right as prophylactic and therapeutic reagents to treat diverse CoVs and as templates for …
[HTML][HTML] Acute respiratory distress syndrome in COVID-19: possible mechanisms and therapeutic management
COVID-19 pandemic is a serious concern in the new era. Acute respiratory distress
syndrome (ARDS), and lung failure are the main lung diseases in COVID-19 patients. Even …
syndrome (ARDS), and lung failure are the main lung diseases in COVID-19 patients. Even …