Epistatic models predict mutable sites in SARS-CoV-2 proteins and epitopes

J Rodriguez-Rivas, G Croce… - Proceedings of the …, 2022 - National Acad Sciences
The emergence of new variants of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) is a major concern given their potential impact on the transmissibility and …

A scalable serology solution for profiling humoral immune responses to SARS‐CoV‐2 infection and vaccination

K Colwill, Y Galipeau, M Stuible… - Clinical & …, 2022 - Wiley Online Library
Objectives Antibody testing against severe acute respiratory syndrome coronavirus 2 (SARS‐
CoV‐2) has been instrumental in detecting previous exposures and analyzing vaccine …

[HTML][HTML] Impact of virus genetic variability and host immunity for the success of COVID-19 vaccines

WG Dos Santos - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Abstract Coronavirus disease 19 (COVID-19) continues to challenge most scientists in the
search of an effective way to either prevent infection or to avoid spreading of the disease. As …

[HTML][HTML] Signatures in SARS-CoV-2 spike protein conferring escape to neutralizing antibodies

M Alenquer, F Ferreira, D Lousa, M Valério… - PLoS …, 2021 - journals.plos.org
Understanding SARS-CoV-2 evolution and host immunity is critical to control COVID-19
pandemics. At the core is an arms-race between SARS-CoV-2 antibody and angiotensin …

A critical review on SARS-CoV-2 infectivity in water and wastewater. What do we know?

A Giacobbo, MAS Rodrigues, JZ Ferreira… - Science of the Total …, 2021 - Elsevier
The COVID-19 outbreak circulating the world is far from being controlled, and possible
contamination routes are still being studied. There are no confirmed cases yet, but little is …

Emerging SARS-CoV-2 variants of concern evade humoral immune responses from infection and vaccination

TG Caniels, I Bontjer, K van der Straten, M Poniman… - Science …, 2021 - science.org
Emerging SARS-CoV-2 variants of concern (VOCs) pose a threat to human immunity
induced by natural infection and vaccination. We assessed the recognition of three VOCs (B …

SARS-CoV-2 antibody responses are correlated to disease severity in COVID-19 convalescent individuals

CB Hansen, I Jarlhelt, L Pérez-Alós… - The Journal of …, 2021 - journals.aai.org
Globally, the COVID-19 pandemic has had extreme consequences for the healthcare system
and has led to calls for diagnostic tools to monitor and understand the transmission …

Infectious Diseases Society of America guidelines on the diagnosis of COVID-19: serologic testing

MK Hayden, IK El Mikati, KE Hanson… - Clinical Infectious …, 2024 - academic.oup.com
Background The role of serologic testing for SARS-CoV-2 has evolved during the pandemic
as seroprevalence in global populations has increased. The Infectious Diseases Society of …

[HTML][HTML] Safety and immunogenicity of the SARS-CoV-2 ARCoV mRNA vaccine in Chinese adults: a randomised, double-blind, placebo-controlled, phase 1 trial

GL Chen, XF Li, XH Dai, N Li, ML Cheng… - The Lancet …, 2022 - thelancet.com
Background Safe and effective vaccines are urgently needed to end the COVID-19
pandemic caused by SARS-CoV-2 infection. We aimed to assess the preliminary safety …

[HTML][HTML] Humoral immune responses and neutralizing antibodies against SARS-CoV-2; implications in pathogenesis and protective immunity

J Carrillo, N Izquierdo-Useros, C Ávila-Nieto… - Biochemical and …, 2021 - Elsevier
The magnitude and the quality of humoral responses against SARS-CoV-2 have been
associated with clinical outcome. Although the elicitation of humoral responses against …