A new DNA‐binding unit of a protein different from the alpha‐helix, the beta‐sheet and the
Zn‐finger is proposed based on the analysis of the structure of the N‐terminus of sea urchin …

▪ Abstract A powerful approach to understanding protein enzyme catalysis is to examine the
structural context of essential amino acid side chains whose deletion or modification …

The three-dimensional structure of the highly thermostable 3-isopropylmalate
dehydrogenase (IPMDH) from Thermus thermophilus has been determined by the multiple …

The RNP domain is a very common eukaryotic protein domain involved in recognition of a
wide range of RNA structures and sequences. Two structures of human U1A in complex with …

The crystal structure of holo-glyceraldehyde-3-phosphate dehydrogenase from the
hyperthermophileThermotoga maritimawas determined by Patterson search methods using …

Buried water molecules and the water molecules in the active-site gorge are analyzed for
five crystal structures of acetylcholinesterase from Torpedo californica in the resolution …

A xylanase belonging to family 10 is produced by Cryptococcus adeliae, an Antarctic yeast
that exhibits optimal growth at low temperature. The mature glycosylated xylanase secreted …

We have generated an extensive genetic map of functionally allowed and/or structurally
allowed amino acid substitutions in Arc repressor, a DNA binding protein of unknown …

In the N‐terminal domain of λ repressor, the Asp 14 side chain forms an intrahelical,
hydrogen bond/salt bridge with the Arg 17 side chain and a tertiary hydrogen bond with the …

The contribution of backbone hydrogen bonds in α-helices to the overall stability of a protein
has been examined experimentally by replacing several backbone amide linkages in α-helix …