We have reported that the region between amino acids 164 and 303 in the glycoprotein of
rabies Nishigahara strain is important for lethality in adult mice. The region contains nine …

In globular proteins, there are intermolecular hydrogen bonds between protein and water
molecules, and between water molecules, which are bound with the proteins, in addition to …

We have set up and manually curated a dataset containing experimental information on the
impact of amino acid substitutions in a protein on its thermal stability. It consists of a …

The overall contribution of hydrogen bonds to the stability of proteins remains an unresolved
issue. 1, 2 Site-directed mutagenesis has been used to experimentally determine the …

The extremely thermostable superoxide dismutase from the hyperthermophilic archaeon
Sulfolobus acidocaldarius was crystallized and the three-dimensional structure was …

MATERIALS AND METHODS Construction and Purification of Subtilisin Variants. Mutants 1
and 3-6 (Figure 1) were produced by site-directed mutagenesis (Zoller & Smith, 1987) of the …

A homology model of the dopamine D2 receptor was constructed based on the crystal
structure of rhodopsin. A putative sodium-binding pocket identified in an earlier model (PDB …

Revised Manuscript Received August 23, 1995® abstract: Hydrogen bonds are a ubiquitous
feature of protein structures, yet there is great uncertainty about the energetic contribution of …

We previously suggested that proteins gain more stability from the burial and hydrogen
bonding of polar groups than from the burial of nonpolar groups (Pace, CN (2001) …

A cell-free system has been developed that executes centriole duplication. Surf clam
(Spisula solidissima) oocytes, arrested at late prophase of meiosis I, do not contain …