Epidemiology and Pathophysiology of Multiple Sclerosis : CONTINUUM: Lifelong Learning in
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Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system that
causes demyelination, axonal degeneration and astrogliosis, resulting in progressive …

Background and Objectives Neurodegeneration and astrocytic activation are pathologic
hallmarks of progressive multiple sclerosis (MS) and can be quantified by serum …

Progressive multiple sclerosis (MS) is a chronic disease with a unique pattern, which is
histologically classified into the subpial type 3 lesions in the autopsy. The lesion is also …

Multiple Sclerosis (MS) is a neuroinflammatory disorder, which is histopathologically
characterized by multifocal inflammatory demyelinating lesions affecting both the central …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS). Astrocytes are the most abundant glial cells in the CNS, and their dysfunction …

Background: Multiple sclerosis (MS) is a multifocal inflammatory central nervous system
disorder. There are now many highly effective disease-modifying therapies (DMTs) available …

Dietary interventions can ameliorate age-related neurological decline. Decades of research
of in vitro studies, animal models, and clinical trials support their ability and efficacy to …

Neuroinflammatory diseases remain a therapeutic challenge, notably when progressing
towards neurodegeneration. In this context, multiple sclerosis represents a central nervous …

Background Multiple sclerosis (MS) leads to demyelination and neurodegeneration with
autoimmune responses in central nervous system. Patients begin with a relapsing–remitting …