ASK1-K716R reduces neuroinflammation and white matter injury via preserving blood–brain barrier integrity after traumatic brain injury

S Meng, H Cao, Y Huang, Z Shi, J Li, Y Wang… - Journal of …, 2023 - Springer
Background Traumatic brain injury (TBI) is a significant worldwide public health concern that
necessitates attention. Apoptosis signal-regulating kinase 1 (ASK1), a key player in various …

Sex-specific effects of buprenorphine on endoplasmic reticulum stress, abnormal protein accumulation, and cell loss after pediatric mild traumatic brain injury in mice

MB Faulkner, M Rizk, Z Bazzi, RC Dysko… - Neurotrauma …, 2023 - liebertpub.com
Traumatic brain injury (TBI) in children often leads to poor developmental outcomes
attributable to progressive cell loss caused by secondary injuries, including endoplasmic …

Adropin may regulate corpus luteum formation and its function in adult mouse ovary

S Maurya, S Tripathi, T Arora, A Singh - Hormones, 2023 - Springer
Background Adropin, a unique peptide hormone, has been associated with the regulation of
several physiological processes, including glucose homeostasis, fatty acid metabolism, and …

Molecular effects of FDA-approved multiple sclerosis drugs on glial cells and neurons of the central nervous system

KMA De Kleijn, GJM Martens - International Journal of Molecular …, 2020 - mdpi.com
Multiple sclerosis (MS) is characterized by peripheral and central inflammatory features, as
well as demyelination and neurodegeneration. The available Food and Drug Administration …

T‐cell infiltration, contribution and regulation in the central nervous system post‐traumatic injury

L Xu, X Ye, Q Wang, B Xu, J Zhong, Y Chen… - Cell …, 2021 - Wiley Online Library
T cells participate in the repair process and immune response in the CNS post‐traumatic
injury and play both a beneficial and harmful role. Together with nerve cells and other …

[HTML][HTML] Secondary white matter injury mediated by neuroinflammation after intracerebral hemorrhage and promising therapeutic strategies of targeting the NLRP3 …

L Xiao, M Wang, Y Shi, Y Xu, Y Gao… - Current …, 2023 - ncbi.nlm.nih.gov
Intracerebral hemorrhage (ICH) is a neurological disease with high mortality and disability.
Recent studies showed that white matter injury (WMI) plays an important role in motor …

Pharmacological inhibition of STING reduces neuroinflammation‐mediated damage post‐traumatic brain injury

AL Fryer, A Abdullah, F Mobilio… - British Journal of …, 2024 - Wiley Online Library
Background and Purpose Traumatic brain injury (TBI) remains a major public health concern
worldwide with unmet effective treatment. Stimulator of interferon genes (STING) and its …

Ontogeny of adropin and its receptor expression during postnatal development and its pro-gonadal role in the ovary of pre-pubertal mouse

S Maurya, S Tripathi, A Singh - The Journal of Steroid Biochemistry and …, 2023 - Elsevier
Adropin, a highly conserved multifunctional peptide hormone, has a beneficial effect on the
maintenance of gluco-lipid homeostasis, endothelial and cardiovascular functions. However …

Evolving brain and behaviour changes in rats following repetitive subconcussive head impacts

WS Hoogenboom, TG Rubin, K Ambadipudi… - Brain …, 2023 - academic.oup.com
There is growing concern that repetitive subconcussive head impacts, independent of
concussion, alter brain structure and function, and may disproportionately affect the …

[HTML][HTML] cGAS-stimulator of interferon genes signaling in central nervous system disorders

F Li, N Wang, Y Zheng, Y Luo, Y Zhang - Aging and disease, 2021 - ncbi.nlm.nih.gov
Cytosolic nucleic acid sensors contribute to the initiation of innate immune responses by
playing a critical role in the detection of pathogens and endogenous nucleic acids. The …