Aims Rasd1 has been reported to be correlated with neurotoxicity, metabolism, and rhythm,
but its effect in case of subarachnoid hemorrhage (SAH) remained unclear. White matter …

Background: Endoplasmic reticulum (ER) stress and unfolded protein response (UPR) is
associated with neuroinflammation and subsequent cell death following traumatic brain …

Background White matter injury (WMI) is a major neuropathological event associated with
intracerebral hemorrhage (ICH). P2X purinoreceptor 4 (P2X4R) is a member of the P2X …

Traumatic brain injury (TBI) is a non-degenerative and non-congenital insult to the brain and
is recognized as a global public health problem, with a high incidence of neurological …

Anxiety is reportedly one of the most common mental changes after traumatic brain injury
(TBI). Perineuronal nets (PNNs) produced by astrocytes in the lateral hypothalamus (LHA) …

Abstract Development of the Central Nervous System (CNS) is reliant on the proper function
of numerous intricately orchestrated mechanisms that mature independently, including …

Glaucoma is a complex neurodegenerative disease leading to a loss of retinal ganglion
cells (RGCs) and optic nerve axons. An activation of the complement system seems to …

Abstract Type-1 IFN (interferon)-associated innate immune response is increasingly getting
attention in neurodegenerative and metabolic diseases like type 2 diabetes (T2DM) …

Accumulating evidence suggests that type I interferon (IFN-I) signaling is a key contributor to
immune cell-mediated neuropathology in neurodegenerative diseases. Recently, we …

Traumatic brain injury (TBI) is a major cause of death and disability worldwide. Survivors
may experience movement disorders, memory loss, and cognitive deficits. However, there is …