Background The objective of this research was to examine the impact of the monocyte-to-
lymphocyte ratio (MLR) on the advancement of hematoma after cerebral contusion. Methods …

Preterm white matter injury (WMI) is a demyelinating disease with high incidence and
mortality in premature infants. Oligodendrocyte cells (OLs) are a specialized glial cell that …

While originally identified as an antiviral pathway, recent work has implicated that cyclic
GMP-AMP-synthase-Stimulator of Interferon Genes (cGAS-STING) signaling is playing a …

Intravenous immunoglobulin (IVIG) is a promising immune-modulatory therapy for limiting
harmful inflammation and associated secondary tissue loss in neurotrauma. Here, we show …

Traumatic brain injury (TBI), as a serious central nervous system disease, can result in
severe neurological dysfunction or even disability and death of patients. The early and …

Background Nocardia is a facultative intracellular pathogen that infects the lungs and brains
of immunocompromised patients with consequences that can be fatal. The incidence of such …

Neuroinflammation plays a key role in the development of depression-like behaviors.
Endoplasmic reticulum (ER) stress, defined as accumulation of unfolded proteins in the ER …

Adropin, a multifaceted peptide, was identified as a new metabolic hormone responsible for
regulating gluco-lipid homeostasis. However, its role in the testicular function is not yet …

Background Inflammation is a significant contributor to neuronal death and dysfunction
following traumatic brain injury (TBI). Recent evidence suggests that interferons may be a …

Aging is associated with cognitive decline and is the main risk factor for a myriad of
conditions including neurodegeneration and stroke. Concomitant with aging is the …