It is important to understand the balance between cortical plasticity and stability in various
systems and across spatial scales in the adult brain. Here we review studies of adult …

Vision loss after retinal or cerebral visual injury (CVI) was long considered to be irreversible.
However, there is considerable potential for vision restoration and recovery even in …

Retinal lesions caused by eye diseases such as glaucoma and age-related macular
degeneration can, over time, eliminate stimulation of parts of the visual cortex. This could …

Electric stimulation of the retina reliably elicits light percepts in patients blinded by outer
retinal diseases. However, individual percepts are highly variable and do not readily …

The functional architecture of adult cerebral cortex retains a capacity for experience-
dependent change. This is seen following focal binocular lesions, which induce rapid …

Amblyopia is a cortically based visual disorder caused by disruption of vision during a
critical early developmental period. It is often thought to be a largely intractable problem in …

Electrophysiological and behavioral studies in many species have demonstrated mirror-
image confusion for objects, perhaps because many objects are vertically symmetric (eg, a …

Several aspects of cortical organization are thought to remain plastic into adulthood,
allowing cortical sensorimotor maps to be modified continuously by experience. This …

Drug development today needs to balance agility, speed and risk in defining the probability
of success for molecules, mechanisms and therapeutic concepts. New techniques in …

Maintaining the strong pedagogy, abundant student-friendly examples, and engaging
conversational style of the previous editions, the sixth edition of this introductory textbook …