Relatively little is known regarding mitochondrial metabolism in neuronal differentiation of
embryonic stem (ES) cells. By using a small molecule, present research has investigated the …

S-P467L mice expressing dominant negative peroxisome proliferator-activated receptor-γ
selectively in vascular smooth muscle exhibit impaired vasodilation, augmented …

The peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription
factors that belong to the nuclear receptor family. It is well known that PPARs function as …

目的探讨罗格列酮对局灶性脑缺血/再灌注损伤的保护作用及其机制. 方法线栓法制备大鼠大脑
中动脉局灶性脑栓塞模型, 缺血2h, 再灌注24h. 评价神经功能状态, 测定脑梗死体积; …

Gestational exposure to a fat-rich diet, while elevating maternal circulating fatty acids,
increases in the offspring's hypothalamus and amygdala the proliferation and density of …

Peroxisome proliferator–activated receptor alpha (PPARα) is a member of the nuclear factor
PPAR family that regulates a variety of cellular functions, including lipid metabolism, cellular …

Background: Alzheimer's disease (AD) is a progressive neurodegenerative disease and
nowadays the role of endothelial cell (EC) injury has been proposed in pathological process …

La regulación de la expresión de los genes está determinada por una serie de moléculas
que en su conjunto modulan la activación o la represión de un gen o de un grupo de genes …

Objectives This study investigated the involvement of different types of K+ channels and
PPAR γ receptors in the antidepressant-like effect of diphenyl diselenide in mice. Methods …

We evaluated the possible effects of long-term fenofibrate treatment on adrenergic, nitrergic
and CGRP-ergic innervation function in mesenteric arteries from streptotozin-induced …