MicroRNA-21's role in PTEN suppression and PI3K/AKT activation: Implications for cancer biology
Abstract MicroRNA-21 (miR-21) was recognized as a key figure in the intricate web of tumor
biology, with a prominent role in regulating the PTEN tumor suppressor gene and the …
biology, with a prominent role in regulating the PTEN tumor suppressor gene and the …
Exploring ncRNA-mediated pathways in sepsis-induced pyroptosis
Sepsis, a potentially fatal illness caused by an improper host response to infection, remains
a serious problem in the world of healthcare. In recent years, the role of ncRNA has …
a serious problem in the world of healthcare. In recent years, the role of ncRNA has …
Circular RNAs in the KRAS pathway: Emerging players in cancer progression
Circular RNAs (circRNAs) have been recognized as key components in the intricate
regulatory network of the KRAS pathway across various cancers. The KRAS pathway, a …
regulatory network of the KRAS pathway across various cancers. The KRAS pathway, a …
Exploring the oncogenic and tumor-suppressive roles of Circ-ADAM9 in cancer
Circular RNAs (circRNAs) constitute a recently identified category of closed continuous loop
RNA transcripts, serving as a subset of competing endogenous RNAs (ceRNAs) with the …
RNA transcripts, serving as a subset of competing endogenous RNAs (ceRNAs) with the …
Overcoming chemoresistance and radio resistance in prostate cancer: The emergent role of non-coding RNAs
M Sarfraz, A Khan, L Eltaib, SMB Asdaq… - … -Research and Practice, 2024 - Elsevier
Prostate cancer (PCa) continues to be a major health concern worldwide, with its resistance
to chemotherapy and radiation therapy presenting major hurdles in successful treatment …
to chemotherapy and radiation therapy presenting major hurdles in successful treatment …
Unravelling the role of long non-coding RNAs in modulating the Hedgehog pathway in cancer
Cancer is a multifactorial pathological condition characterized by uncontrolled cellular
proliferation, genomic instability, and evasion of regulatory mechanisms. It arises from the …
proliferation, genomic instability, and evasion of regulatory mechanisms. It arises from the …
From diagnosis to therapy: The critical role of lncRNAs in hepatoblastoma
AK Alzahrani, A Khan, N Singla, A Hai… - … -Research and Practice, 2024 - Elsevier
According to findings, long non-coding RNAs (lncRNAs) serves an integral part in growth
and development of a variety of human malignancies, including Hepatoblastoma (HB). HB is …
and development of a variety of human malignancies, including Hepatoblastoma (HB). HB is …
Noncoding RNAs as Therapeutic Targets in Autophagy-Related Diabetic Cardiomyopathy
Diabetic cardiomyopathy, a multifaceted complication of diabetes mellitus, remains a major
challenge in clinical management due to its intricate pathophysiology. Emerging evidence …
challenge in clinical management due to its intricate pathophysiology. Emerging evidence …
The Dual Roles of circRNAs in Wnt/β-Catenin Signaling and Cancer Progression
WH Almalki, SS Almujri - Pathology-Research and Practice, 2024 - Elsevier
Cancer, a complex pathophysiological condition, arises from the abnormal proliferation and
survival of cells due to genetic mutations. Dysregulation of cell cycle control, apoptosis, and …
survival of cells due to genetic mutations. Dysregulation of cell cycle control, apoptosis, and …
Targeting the autophagy-miRNA axis in prostate cancer: toward novel diagnostic and therapeutic strategies
Since prostate cancer is one of the leading causes of cancer-related death, a better
understanding of the molecular pathways guiding its development is imperative. A key factor …
understanding of the molecular pathways guiding its development is imperative. A key factor …