NLRP3 inflammasome at the interface of inflammation, endothelial dysfunction, and type 2 diabetes

IM Gora, A Ciechanowska, P Ladyzynski - Cells, 2021 - mdpi.com
Type 2 diabetes mellitus (T2DM), accounting for 90–95% cases of diabetes, is characterized
by chronic inflammation. The mechanisms that control inflammation activation in T2DM are …

Pathophysiology of type 2 diabetes in children and adolescents

B Valaiyapathi, B Gower, AP Ashraf - Current diabetes reviews, 2020 - ingentaconnect.com
Background: The prevalence of type 2 diabetes (DM) in children is disturbingly increasing in
parallel with the increasing childhood obesity. Better knowledge regarding the …

Fecal fermentation and high-fat diet-induced obesity mouse model confirmed exopolysaccharide from Weissella cibaria PFY06 can ameliorate obesity by regulating …

Y Xie, F Pei, Y Liu, Z Liu, X Chen, D Xue - Carbohydrate Polymers, 2023 - Elsevier
Obesity associated with diet and intestinal dysbiosis is a worldwide public health crisis, and
exopolysaccharides (EPS) produced by lactic acid bacteria (LAB) have prebiotic potential to …

Risk of developing type 2 diabetes in adolescents and young adults with autism spectrum disorder: a nationwide longitudinal study

MH Chen, WH Lan, JW Hsu, KL Huang, TP Su… - Diabetes …, 2016 - Am Diabetes Assoc
OBJECTIVE Studies have suggested the association between autism spectrum disorder
(ASD) and type 2 diabetes mellitus (DM)–related risk factors, such as obesity and …

Positive effects of physical activity in autism spectrum disorder: how influences behavior, metabolic disorder and gut microbiota

A Ranieri, C Mennitti, N Falcone, I La Monica… - Frontiers in …, 2023 - frontiersin.org
Autism spectrum disorder is a neurodevelopmental disorder characterized by social
interactions and communication skills impairments that include intellectual disabilities …

Disease-induced neuroinflammation and depression

C Benatti, J MC Blom, G Rigillo, S Alboni… - CNS & Neurological …, 2016 - ingentaconnect.com
Progression of major depression, a multifactorial disorder with a neuroinflammatory
signature, seems to be associated with the disruption of body allostasis. High rates of …

Effects of carnosine and histidine-containing dipeptides on biomarkers of inflammation and oxidative stress: a systematic review and meta-analysis

S Saadati, RH Kabthymer, G Aldini, A Mousa… - Nutrition …, 2023 - academic.oup.com
Context Carnosine and histidine-containing dipeptides (HCDs) are suggested to have anti-
inflammatory and antioxidative benefits, but their effects on circulating adipokines and …

Hesperidin ameliorates pancreatic β-cell dysfunction and apoptosis in streptozotocin-induced diabetic rat model

W Hanchang, A Khamchan, N Wongmanee… - Life sciences, 2019 - Elsevier
Aims The current study was conducted to investigate the potential protective effects of
hesperidin and its possible mechanisms of action on pancreatic β-cells in diabetes. Main …

Protective role of mitoquinone against impaired mitochondrial homeostasis in metabolic syndrome

J Yang, H Suo, J Song - Critical reviews in food science and …, 2021 - Taylor & Francis
Mitochondria control various processes in cellular metabolic homeostasis, such as
adenosine triphosphate production, generation and clearance of reactive oxygen species …

Life and death of β cells in Type 1 diabetes: A comprehensive review

NS Wilcox, J Rui, M Hebrok, KC Herold - Journal of autoimmunity, 2016 - Elsevier
Abstract Type 1 diabetes (T1D) is an autoimmune disorder characterized by the destruction
of insulin-producing pancreatic β cells. Immune modulators have achieved some success in …