Cell-free DNA (cfDNA) derived from tumours is present in the plasma of cancer patients. The
majority of currently available studies on the use of this circulating tumour DNA (ctDNA) deal …

Carcinogenesis is accompanied by widespread DNA methylation changes within the cell.
These changes are characterized by a globally hypomethylated genome with focal …

Hepatocellular carcinoma (HCC) is one of the most common cancers and a leading cause of
death worldwide. Due to latent liver disease, late diagnosis, and nonresponse to systemic …

Plasma cell-free DNA (cfDNA) are small molecules generated through a non-random
fragmentation procedure. Despite commendable translational values in cancer liquid biopsy …

Recurrence of meningiomas is unpredictable by current invasive methods based on
surgically removed specimens. Identification of patients likely to recur using noninvasive …

Purpose To explore whether targeted next generation sequencing (NGS) of liquid biopsy in
advanced non-small cell lung cancer (NSCLC) could potentially overcome the innate …

Gasdermin E (GSDME), a gene originally involved in hereditary hearing loss, has been
associated with several types of cancer in the last two decades. Recently, GSDME was …

Evanescent-wave optical biosensors have become an attractive alternative for the screening
of nucleic acids in the clinical context. They possess highly sensitive transducers able to …

Epigenetic alterations pose one major hallmark of organismal aging. Here, we provide an
overview on recent findings describing the epigenetic changes that arise during aging and …

Colorectal cancer (CRC) is one of the most common human malignancies accounting for
approximately 10% of worldwide cancer incidence and mortality. While early-stage CRC is …