Gold nanoparticles as novel agents for cancer therapy

S Jain, DG Hirst, JM O'Sullivan - The British journal of radiology, 2012 - academic.oup.com
Gold nanoparticles are emerging as promising agents for cancer therapy and are being
investigated as drug carriers, photothermal agents, contrast agents and radiosensitisers …

[HTML][HTML] Nanoparticles for radiation therapy enhancement: the key parameters

P Retif, S Pinel, M Toussaint, C Frochot, R Chouikrat… - Theranostics, 2015 - ncbi.nlm.nih.gov
This review focuses on the radiosensitization strategies that use high-Z nanoparticles. It
does not establish an exhaustive list of the works in this field but rather propose constructive …

Physical basis and biological mechanisms of gold nanoparticle radiosensitization

KT Butterworth, SJ McMahon, FJ Currell, KM Prise - Nanoscale, 2012 - pubs.rsc.org
The unique properties of nanomaterials, in particular gold nanoparticles (GNPs) have
applications for a wide range of biomedical applications. GNPs have been proposed as …

Gold nanoparticles as radiation sensitizers in cancer therapy

DB Chithrani, S Jelveh, F Jalali… - Radiation …, 2010 - meridian.allenpress.com
Among other nanoparticle systems, gold nanoparticles have been explored as
radiosensitizers. While most of the research in this area has focused on either gold …

Gold nanoparticle imaging and radiotherapy of brain tumors in mice

JF Hainfeld, HM Smilowitz, MJ O 'Connor… - …, 2013 - Taylor & Francis
Aim: To test intravenously injected gold nanoparticles for x-ray imaging and radiotherapy
enhancement of large, imminently lethal, intracerebral malignant gliomas. Materials & …

Cell-specific radiosensitization by gold nanoparticles at megavoltage radiation energies

S Jain, JA Coulter, AR Hounsell, KT Butterworth… - International Journal of …, 2011 - Elsevier
PURPOSE: Gold nanoparticles (GNPs) have been shown to cause sensitization with
kilovoltage (kV) radiation. Differences in the absorption coefficient between gold and soft …

Nanoparticles as contrast agents for in-vivo bioimaging: current status and future perspectives

MA Hahn, AK Singh, P Sharma, SC Brown… - Analytical and …, 2011 - Springer
Nanoparticle-based contrast agents are quickly becoming valuable and potentially
transformative tools for enhancing medical diagnostics for a wide range of in-vivo imaging …

Roadmap for metal nanoparticles in radiation therapy: Current status, translational challenges, and future directions

J Schuemann, AF Bagley, R Berbeco… - Physics in Medicine …, 2020 - iopscience.iop.org
This roadmap outlines the potential roles of metallic nanoparticles (MNPs) in the field of
radiation therapy. MNPs made up of a wide range of materials (from Titanium, Z= 22, to …

Biological consequences of nanoscale energy deposition near irradiated heavy atom nanoparticles

SJ McMahon, WB Hyland, MF Muir, JA Coulter… - Scientific reports, 2011 - nature.com
Gold nanoparticles (GNPs) are being proposed as contrast agents to enhance X-ray
imaging and radiotherapy, seeking to take advantage of the increased X-ray absorption of …

Engineering gold-based radiosensitizers for cancer radiotherapy

N Goswami, Z Luo, X Yuan, DT Leong, J Xie - Materials Horizons, 2017 - pubs.rsc.org
Radiotherapy remains a major modality in cancer therapy. The main goal of radiotherapy is
to shrink tumors and kill cancer cells by using high-energy radiation, such as X-rays and γ …