Role of inflammatory cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to …

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is a severe pandemic of the current century. The vicious …

COVID-19: characteristics and therapeutics

R Chilamakuri, S Agarwal - Cells, 2021 - mdpi.com
Novel coronavirus (COVID-19 or 2019-nCoV or SARS-CoV-2), which suddenly emerged in
December 2019 is still haunting the entire human race and has affected not only the …

Endothelial Dysfunction, Inflammation, and Oxidative Stress in COVID‐19—Mechanisms and Therapeutic Targets

A Fodor, B Tiperciuc, C Login… - Oxidative medicine …, 2021 - Wiley Online Library
The outbreak of the COVID‐19 pandemic represents an ongoing healthcare emergency
responsible for more than 3.4 million deaths worldwide. COVID‐19 is the disease caused by …

[HTML][HTML] COVID-19-associated acute respiratory distress syndrome (CARDS): Current knowledge on pathophysiology and ICU treatment–A narrative review

CA Pfortmueller, T Spinetti, RD Urman… - Best Practice & …, 2021 - Elsevier
Abstract (163 words) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
induces coronavirus-19 disease (COVID-19) and is a major health concern. Following two …

Diverse immunological factors influencing pathogenesis in patients with COVID-19: a review on viral dissemination, immunotherapeutic options to counter cytokine …

AA Rabaan, SH Al-Ahmed, MA Garout, AM Al-Qaaneh… - Pathogens, 2021 - mdpi.com
The pathogenesis of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is still not fully unraveled. Though …

Deep learning in target prediction and drug repositioning: Recent advances and challenges

JL Yu, QQ Dai, GB Li - Drug Discovery Today, 2022 - Elsevier
Highlights•Basic principles of commonly used deep learning architectures.•Drug–target
interactions based deep learning approaches for drug repositioning.•Heterogeneous …

A review on structural, non-structural, and accessory proteins of SARS-CoV-2: Highlighting drug target sites

MJ Islam, NN Islam, MS Alom, M Kabir, MA Halim - Immunobiology, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
COVID-19, is a highly transmittable and pathogenic human coronavirus that first emerged in …

Immunogenicity of candidate MERS-CoV DNA vaccines based on the spike protein

SS Al-Amri, AT Abbas, LA Siddiq, A Alghamdi… - Scientific reports, 2017 - nature.com
MERS-coronavirus is a novel zoonotic pathogen which spread rapidly to> 25 countries since
2012. Its apparent endemicity and the wide spread of its reservoir host (dromedary camels) …

[HTML][HTML] A detailed review of the outbreak of COVID-19

K Das, MS Pingali, B Paital, F Panda… - Frontiers in Bioscience …, 2021 - imrpress.com
The disease COVID-19 caused by SARS-CoV-2 is the third highly infectious human
Coronavirus epidemic in the 21s⁢ t century due to its high transmission rate and quick …

[HTML][HTML] COVID19 associated mucormycosis: Is GRP78 a possible link?

J Gumashta, R Gumashta - Journal of Infection and Public Health, 2021 - Elsevier
This review aimed to study molecular mechanisms for high incidence of life-threatening
mucormycosis infection in COVID19 cases during second wave of SARS CoV2 pandemic in …