[HTML][HTML] Pleiotropy of Progesterone Receptor Membrane Component 1 in Modulation of Cytochrome P450 Activity
IS Barata, J Rueff, M Kranendonk, F Esteves - Journal of xenobiotics, 2024 - mdpi.com
Progesterone receptor membrane component 1 (PGRMC1) is one of few proteins that have
been recently described as direct modulators of the activity of human cytochrome P450 …
been recently described as direct modulators of the activity of human cytochrome P450 …
Asparagine-85 Stabilizes a Structural Active Site Water Network in CYP121A1 of Mycobacterium tuberculosis
CS Campomizzi, PP Uttamrao, JJ Stallone… - Biochemistry, 2024 - ACS Publications
The cytochrome P450 enzyme CYP121A1 endogenously catalyzes the formation of a
carbon–carbon bond between the two phenol groups of dicyclotyrosine (cYY) in …
carbon–carbon bond between the two phenol groups of dicyclotyrosine (cYY) in …
[HTML][HTML] Single mutations in cytochrome P450 oxidoreductase can alter the specificity of human cytochrome P450 1A2-mediated caffeine metabolism
F Esteves, CMM Almeida, S Silva, I Saldanha, P Urban… - Biomolecules, 2023 - mdpi.com
A unique cytochrome P450 (CYP) oxidoreductase (CPR) sustains activities of human
microsomal CYPs. Its function requires toggling between a closed conformation enabling …
microsomal CYPs. Its function requires toggling between a closed conformation enabling …