[HTML][HTML] Defining interactions between the genome, epigenome, and the environment in inflammatory bowel disease: progress and prospects

AJ Noble, JK Nowak, AT Adams, HH Uhlig, J Satsangi - Gastroenterology, 2023 - Elsevier
Recent advances in our understanding of the pathogenesis of inflammatory bowel disease
(IBD) have highlighted the complex interplay between the genome, the epigenome, and the …

Interactions between circRNAs and miR-141 in cancer: from pathogenesis to diagnosis and therapy

M Guz, W Jeleniewicz, M Cybulski - International Journal of Molecular …, 2023 - mdpi.com
The function of non-coding RNAs (ncRNAs) in the pathogenesis and development of cancer
is indisputable. Molecular mechanisms underlying carcinogenesis involve the aberrant …

Research hotspot and trend analysis in the diagnosis of inflammatory bowel disease: a machine learning bibliometric analysis from 2012 to 2021

C Liu, R Yu, J Zhang, S Wei, F Xue, Y Guo… - Frontiers in …, 2022 - frontiersin.org
Aims This study aimed to conduct a bibliometric analysis of the relevant literature on the
diagnosis of inflammatory bowel disease (IBD), and show its current status, hot spots, and …

Drugst. One—a plug-and-play solution for online systems medicine and network-based drug repurposing

A Maier, M Hartung, M Abovsky… - Nucleic Acids …, 2024 - academic.oup.com
In recent decades, the development of new drugs has become increasingly expensive and
inefficient, and the molecular mechanisms of most pharmaceuticals remain poorly …

Current and emerging biomarkers for ulcerative colitis

JK Nowak, R Kalla, J Satsangi - Expert Review of Molecular …, 2023 - Taylor & Francis
Introduction Ulcerative colitis (UC) is a chronic illness requiring lifelong management that
could be enhanced by personalizing care using biomarkers. Areas covered The main …

miRNA molecules—late breaking treatment for inflammatory bowel diseases?

I Aggeletopoulou, A Mouzaki, K Thomopoulos… - International Journal of …, 2023 - mdpi.com
MicroRNAs (miRNAs) are a group of non-coding RNAs that play a critical role in regulating
epigenetic mechanisms in inflammation-related diseases. Inflammatory bowel diseases …

[HTML][HTML] Multi-omics in Crohn's disease: New insights from inside

C Mu, Q Zhao, Q Zhao, L Yang, X Pang, T Liu… - Computational and …, 2023 - Elsevier
Crohn's disease (CD) is an inflammatory bowel disease (IBD) with complex clinical
manifestations such as chronic diarrhea, weight loss and hematochezia. Despite the …

Differential expression of serum miR-486 and miR-25 in ulcerative colitis and Crohn's disease: Correlations with disease activity, extent, and location

SA Abdelazim, OG Shaker, O Ali, M El-Tawil… - … -Research and Practice, 2023 - Elsevier
Novel reliable biomarkers of inflammatory bowel disease (IBD) are clinically imperative due
to potential limitations of endoscopic techniques. MicroRNAs (miRNAs) have emerged as …

Serum long noncoding RNA H19/micro RNA-675-5p axis as a probable diagnostic biomarker in inflammatory bowel disease

OG Shaker, A Safa, A Khairy, NF Abozeid - Molecular Biology Reports, 2023 - Springer
Background A significant body of research strengthens the starring role of long non-coding
RNAs (lncRNAs) and microRNAs (miRNAs) in the pathogenesis of inflammatory bowel …

Dynamic changes in extracellular vesicle-associated miRNAs elicited by ultrasound in inflammatory bowel disease patients

F Tran, A Scharmacher, N Baran, N Mishra… - Scientific Reports, 2024 - nature.com
Blood-based biomarkers that reliably indicate disease activity in the intestinal tract are an
important unmet need in the management of patients with IBD. Extracellular vesicles (EVs) …